BBC vs. INNO ETF Comparison

Comparison of Virtus LifeSci Biotech Clinical Trials ETF (BBC) to Harbor Disruptive Innovation ETF (INNO)

BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description

The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$26.09

Average Daily Volume

4,123

Number of Holdings ^*

* may have additional holdings in another (foreign) market

INNO

Harbor Disruptive Innovation ETF

INNO Description

INNO invests in stocks of any size with growth potential linked to disruptive innovation. The fund aims to achieve enhanced risk-adjusted investment outcome by utilizing an active multi-manager approach in which the advisor allocates assets among subadvisors. Each subadvisor represents a strategy that targets associated disruptive companies in technology, advanced therapies, analog-to-digital transition, structural changes and secular trends, and products or services with large demand. The advisor determines and adjusts allocations based on qualitative and quantitative assessments of each strategy, as well as in combination. The fund may invest up to 25% in foreign markets, including developing countries. INNO utilizes the same investment strategy and portfolio management team as its mutual fund counterpart, Harbor Disruptive Innovation Fund.

Grade (RS Rating)

Last Trade

$14.97

Average Daily Volume

2,520

Number of Holdings ^*

* may have additional holdings in another (foreign) market

Performance

Period	BBC	INNO
30 Days	-10.43%	-8.26%
60 Days	-16.77%	-8.62%
90 Days	2.80%	1.88%
12 Months	10.76%	23.19%

14 Overlapping Holdings

Symbol	Grade	Weight in BBC	Weight in INNO	Overlap
ALLO	F	1.05%	0.33%	0.33%
ARVN	D	0.81%	0.83%	0.81%
ARWR	F	0.7%	0.64%	0.64%
BCYC	C	1.28%	0.85%	0.85%
IOVA	C	1.3%	1.12%	1.12%
KRYS	D	1.18%	1.34%	1.18%
KYMR	D	1.19%	0.74%	0.74%
NTLA	D	0.57%	0.38%	0.38%
PCVX	D	0.85%	0.17%	0.17%
QURE	F	0.5%	0.17%	0.17%
RCKT	F	0.71%	1.6%	0.71%
REPL	F	0.7%	0.3%	0.3%
RGNX	F	0.65%	0.72%	0.65%
RNA	A	2.65%	0.94%	0.94%

BBC Overweight 76 Positions Relative to INNO

Symbol	Grade	Weight
ALPN	A	2.89%
VKTX	B	2.86%
VERA	D	2.27%
DYN	C	1.82%
SANA	C	1.72%
CGEM	A	1.66%
CYTK	D	1.52%
LQDA	D	1.5%
MGNX	D	1.48%
KROS	D	1.38%
MRUS	C	1.37%
NRIX	D	1.34%
GERN	A	1.34%
KURA	C	1.33%
FDMT	D	1.26%
COGT	F	1.19%
SMMT	C	1.19%
MLYS	C	1.17%
RVMD	A	1.17%
PTGX	D	1.09%
CRNX	A	1.07%
INBX	D	1.05%
LYEL	D	1.02%
IGMS	D	1.0%
DAWN	A	0.99%
ALXO	A	0.99%
IDYA	C	0.97%
PGEN	F	0.94%
ARDX	D	0.93%
ACLX	D	0.9%
IMTX	F	0.9%
CMPS	C	0.9%
SNDX	C	0.89%
CLDX	D	0.88%
PHAT	F	0.86%
ITOS	D	0.86%
ANAB	B	0.85%
ARCT	F	0.84%
XENE	C	0.84%
MORF	F	0.82%
ORIC	D	0.81%
AKRO	F	0.8%
MDGL	D	0.78%
RCUS	D	0.74%
DVAX	F	0.73%
XNCR	C	0.73%
NUVL	C	0.72%
BLTE	C	0.71%
ZNTL	F	0.71%
ETNB	F	0.7%
OLMA	D	0.69%
RXRX	D	0.68%
VIR	F	0.68%
BEAM	F	0.67%
TGTX	D	0.67%
SRRK	C	0.67%
BMEA	F	0.66%
PLRX	F	0.63%
NVAX	F	0.62%
VRDN	F	0.62%
TERN	F	0.61%
ABCL	F	0.61%
DNLI	F	0.59%
SAVA	B	0.58%
IMVT	F	0.57%
ALEC	F	0.56%
CRBU	F	0.55%
CABA	F	0.55%
RLAY	D	0.5%
PRTA	F	0.45%
EDIT	F	0.43%
VERV	F	0.41%
IRON	F	0.39%
CVAC	F	0.38%
RAPT	F	0.35%
ALLK	F	0.28%

BBC Underweight 67 Positions Relative to INNO

Symbol	Grade	Weight
LRCX	C	-3.73%
NOW	D	-2.97%
GOOG	A	-2.88%
PGR	A	-2.66%
NVDA	B	-2.59%
LIN	C	-2.44%
CDNS	D	-2.41%
AMD	C	-2.38%
AMZN	C	-2.37%
DHR	B	-2.33%
SHOP	D	-2.28%
TXN	A	-2.1%
URI	C	-2.04%
MELI	C	-2.03%
DASH	C	-1.99%
MSFT	C	-1.81%
DXCM	B	-1.8%
ASND	D	-1.72%
GOOGL	A	-1.69%
CRM	D	-1.65%
IOT	B	-1.61%
NET	C	-1.58%
PCOR	D	-1.57%
META	D	-1.46%
AUTL	F	-1.42%
CMG	A	-1.42%
AMAT	C	-1.17%
HUBS	B	-1.09%
TOST	B	-1.08%
DDOG	B	-1.0%
CGNX	B	-1.0%
TMO	B	-0.95%
SNOW	D	-0.95%
GTLS	D	-0.92%
MRNA	A	-0.9%
LSCC	F	-0.84%
CTLT	C	-0.79%
ICLR	D	-0.72%
UBER	D	-0.71%
CCCC	D	-0.7%
NICE	D	-0.67%
TEAM	F	-0.65%
BSY	A	-0.61%
GTLB	F	-0.61%
SMAR	F	-0.58%
MDB	D	-0.58%
PANW	A	-0.57%
INSP	A	-0.51%
DT	F	-0.51%
LLY	B	-0.5%
WDAY	D	-0.48%
MNDY	C	-0.48%
LEGN	F	-0.43%
DKNG	D	-0.41%
ZS	F	-0.41%
SQ	D	-0.41%
OKTA	D	-0.41%
SAP	C	-0.4%
S	C	-0.4%
HUBB	D	-0.38%
IDXX	D	-0.38%
SE	A	-0.34%
PODD	D	-0.28%
LNTH	A	-0.25%
RPTX	F	-0.19%
ADAP	C	-0.17%
FATE	F	-0.11%

BBC: Top Represented Industries & Keywords

Industries: Biotechnology Diagnostics & Research Drug Manufacturers - Specialty & Generic Medical Care Facilities

INNO: Top Represented Industries & Keywords

Industries: Biotechnology Software - Application Diagnostics & Research Software - Infrastructure Semiconductors Internet Content & Information Medical Devices Semiconductor Equipment & Materials Specialty Retail Drug Manufacturers - Major Drug Manufacturers - Specialty & Generic Electronic Components Electronic Gaming & Multimedia Gambling Insurance - Property & Casualty Internet Content & Information Metal Fabrication Rental & Leasing Services Restaurants Scientific & Technical Instruments