XBI vs. FXH ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to First Trust Health Care AlphaDEX (FXH)

XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$94.30

Average Daily Volume

8,465,460

Number of Holdings ^*

128

* may have additional holdings in another (foreign) market

FXH

First Trust Health Care AlphaDEX

FXH Description

The investment seeks investment results that correspond generally to the price and yield (before the fund's fees and expenses) of an equity index called the StrataQuant(R) Health Care Index. The fund will normally invest at least 90% of its net assets in common stocks that comprise the index. The index is a modified equal-dollar weighted index designed by NYSE Euronext to objectively identify and select stocks from the Russell 1000(R) Index in the health care sector that may generate positive alpha relative to traditional passive-style indices through the use of the AlphaDEX(R) selection methodology. It is non-diversified.

Grade (RS Rating)

Last Trade

$108.83

Average Daily Volume

31,179

Number of Holdings ^*

* may have additional holdings in another (foreign) market

Performance

Period	XBI	FXH
30 Days	-4.04%	-0.29%
60 Days	-7.18%	-3.20%
90 Days	-7.09%	-3.77%
12 Months	29.73%	13.28%

14 Overlapping Holdings

Symbol	Grade	Weight in XBI	Weight in FXH	Overlap
ABBV	F	2.33%	0.74%	0.74%
ALNY	D	2.38%	2.14%	2.14%
AMGN	F	2.28%	0.79%	0.79%
BIIB	F	2.19%	1.46%	1.46%
BMRN	F	1.98%	0.4%	0.4%
EXAS	D	2.05%	1.02%	1.02%
EXEL	B	1.23%	2.31%	1.23%
INCY	C	3.29%	1.61%	1.61%
NTRA	A	3.3%	2.72%	2.72%
RARE	F	0.69%	1.96%	0.69%
REGN	F	1.8%	1.02%	1.02%
ROIV	C	1.18%	2.3%	1.18%
UTHR	C	2.88%	2.46%	2.46%
VRTX	D	2.62%	0.89%	0.89%

XBI Overweight 114 Positions Relative to FXH

Symbol	Grade	Weight
GILD	C	2.9%
NBIX	C	2.62%
INSM	C	2.43%
SRPT	F	2.28%
MDGL	B	2.17%
VKTX	F	2.0%
CYTK	F	1.79%
BPMC	B	1.69%
CRSP	D	1.63%
TGTX	B	1.62%
MRNA	F	1.57%
RVMD	C	1.46%
RNA	C	1.32%
KRYS	C	1.29%
HALO	F	1.27%
ADMA	B	1.23%
ALKS	C	1.13%
IONS	F	1.08%
TWST	F	0.93%
PCVX	D	0.9%
IOVA	F	0.88%
BBIO	F	0.87%
APLS	F	0.86%
GERN	D	0.86%
CRNX	C	0.84%
ACLX	C	0.79%
DYN	F	0.78%
ACAD	C	0.78%
SWTX	C	0.77%
AGIO	C	0.76%
BEAM	D	0.72%
RXRX	F	0.66%
PTCT	B	0.64%
FOLD	F	0.63%
IMVT	F	0.62%
RYTM	C	0.61%
NUVL	C	0.6%
NTLA	F	0.58%
PTGX	D	0.58%
VERA	C	0.57%
MIRM	B	0.57%
ARWR	D	0.54%
IDYA	F	0.53%
VCYT	B	0.53%
JANX	C	0.51%
SRRK	C	0.49%
DVAX	C	0.49%
NVAX	F	0.47%
ARDX	F	0.47%
VCEL	B	0.46%
DNLI	D	0.46%
KYMR	D	0.45%
SNDX	F	0.44%
AKRO	B	0.43%
CGON	F	0.42%
ARQT	B	0.42%
BCRX	D	0.42%
CPRX	C	0.41%
KROS	D	0.36%
IRON	B	0.34%
MNKD	C	0.34%
CLDX	F	0.34%
NRIX	C	0.33%
SMMT	D	0.33%
VRDN	D	0.3%
RCKT	F	0.28%
DAWN	D	0.28%
MYGN	F	0.27%
IRWD	F	0.26%
TVTX	C	0.26%
CGEM	F	0.25%
CDNA	D	0.24%
KURA	F	0.24%
XNCR	B	0.24%
APLT	C	0.22%
CDMO	A	0.22%
RCUS	F	0.2%
VIR	D	0.2%
EBS	C	0.2%
REPL	D	0.18%
HUMA	F	0.18%
ALT	C	0.18%
SPRY	C	0.18%
AVXL	B	0.17%
ARCT	F	0.17%
ANNX	F	0.16%
STOK	F	0.16%
ETNB	C	0.16%
MDXG	B	0.16%
COGT	D	0.16%
VERV	F	0.15%
RLAY	F	0.14%
OLMA	F	0.13%
IMNM	F	0.13%
PRTA	F	0.13%
OCGN	F	0.12%
ANAB	F	0.12%
FDMT	F	0.12%
SANA	F	0.12%
RGNX	D	0.12%
ALLO	F	0.11%
CELC	F	0.11%
SAGE	F	0.11%
CCCC	F	0.1%
ERAS	C	0.1%
ORIC	F	0.09%
FATE	F	0.08%
SVRA	F	0.08%
ABUS	D	0.07%
KALV	F	0.07%
SCLX	F	0.06%
YMAB	F	0.06%
ITOS	F	0.06%
ALEC	F	0.04%

XBI Underweight 63 Positions Relative to FXH

Symbol	Grade	Weight
DOCS	C	-2.73%
PINC	B	-2.6%
PODD	C	-2.56%
JAZZ	B	-2.55%
THC	D	-2.23%
RMD	C	-2.16%
DVA	C	-2.15%
UHS	D	-2.0%
HCA	F	-1.94%
CAH	B	-1.88%
ISRG	A	-1.87%
VTRS	A	-1.86%
CNC	D	-1.78%
UNH	B	-1.74%
ZBH	C	-1.73%
DGX	A	-1.73%
CRL	D	-1.71%
ITCI	C	-1.64%
CI	D	-1.6%
RPRX	D	-1.55%
HUM	C	-1.53%
MOH	F	-1.52%
GEHC	D	-1.51%
ENOV	C	-1.45%
EHC	B	-1.43%
PRGO	C	-1.41%
OGN	F	-1.37%
EW	C	-1.37%
ELV	F	-1.34%
MDT	D	-1.31%
HOLX	D	-1.3%
CHE	D	-1.28%
JNJ	C	-1.28%
HSIC	C	-1.25%
LLY	F	-1.22%
INSP	D	-1.12%
WST	C	-0.96%
SYK	B	-0.91%
LH	B	-0.91%
WAT	C	-0.9%
ABT	B	-0.86%
BDX	F	-0.81%
AMED	F	-0.8%
ZTS	D	-0.77%
A	D	-0.75%
TMO	F	-0.74%
IQV	F	-0.73%
BRKR	D	-0.68%
TFX	F	-0.66%
MASI	B	-0.51%
PEN	B	-0.51%
VEEV	C	-0.47%
MEDP	D	-0.43%
RCM	A	-0.43%
TECH	F	-0.39%
RVTY	F	-0.39%
STE	D	-0.39%
DHR	F	-0.37%
ALGN	D	-0.37%
BAX	F	-0.36%
AVTR	F	-0.35%
XRAY	F	-0.28%
TXG	F	-0.27%