Technical Analysis for IONS - Ionis Pharmaceuticals, Inc.

Grade Last Price % Change Price Change
grade B 48.0 -2.06% -1.01
IONS closed down 2.06 percent on Friday, April 3, 2020, on approximately normal volume. The stock exhibited some range contraction during this trading session as price made an NR7 -- narrowest range of the last seven sessions.

Trend Table & Recent Signals

ADX Long Term Intermediate Term Short Term
Strong Down Down Up
Historical IONS trend table...

Date Alert Name Type % Chg
1,2,3 Retracement Bearish Bearish Swing Setup 0.00%
Non-ADX 1,2,3,4 Bearish Bearish Swing Setup 0.00%
Narrow Range Bar Range Contraction 0.00%
NR7 Range Contraction 0.00%
Crossed Above 20 DMA Bullish -2.06%
20 DMA Resistance Bearish 2.54%
Outside Day Range Expansion 2.54%
Down 3 Days in a Row Weakness 2.54%
Down 4 Days in a Row Weakness 2.54%
Fell Below 20 DMA Bearish 1.52%

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Ionis Pharmaceuticals, Inc., a RNA-targeted drug discovery and development company, focuses on developing drugs for patients with severe and rare diseases. It markets KYNAMRO for the treatment of homozygous familial hypercholesterolemia. The company's drugs in Phase III development include volanesorsen for the treatment of patients with familial chylomicronemia syndrome and familial partial lipodystrophy; IONIS-TTRRx, a drug for the treatment of patients with various forms of TTR amyloidosis, including familial amyloid polyneuropathy, familial amyloid cardiomyopathy, and wild-type TTR amyloidosis; and nusinersen, a drug for the treatment of infants and children with spinal muscular atrophy. It is also developing Custirsen, which is in two Phase III studies to treat cancer; and Plazomicin that is Phase III study for the treatment of severe bacterial infection. In addition, the company is developing products, which are Phase II clinical trials include IONIS-DMPK-2.5Rx for myotonic dystrophy type 1; IONIS-HTTR for huntington's disease; ATL1103 for acromegaly; IONIS-FXIRx (BAY 2306001) for clotting disorders; IONIS-APO(a)-LRx for high Lp; IONIS-ANGPTL3-LRx for mixed dyslipidemias; Apatorsen (OGX-427) and IONIS-STAT3-2.5Rx (AZD9150) for cancers; EXC 001 (PF-06473871) for scarring; ATL1102 for multiple sclerosis; and RG-101 for hepatitis C virus infection, as well as products for the treatment of diabetes and obesity. Further, its products in Phase I clinical include IONIS-GCCRRx for cushing's syndrome; IONIS-PKKRx for hereditary angioedema; RG-012 for alport syndrome; IONIS-AR-2.5Rx (AZD5312) for prostate cancer; IONIS-HBVRx for hepatitis B virus infection; IONIS-GSK4-LRx for ocular disease; and IONIS-DGAT2Rx for nonalcoholic steatohepatitis. The company was formerly known as Isis Pharmaceuticals, Inc. and changed its name to Ionis Pharmaceuticals, Inc. in December 2015. Ionis Pharmaceuticals, Inc. was founded in 1989 and is headquartered in Carlsbad, California.
Cancer Organ Systems Diabetes Cancers Drug Discovery Prostate Cancer Disorders Multiple Sclerosis Obesity Genetics Neurological Disorders Huntington's Disease Spinal Muscular Atrophy Treatment Of Diabetes Orphan Drugs Acromegaly Cushing's Syndrome Hepatitis C Virus Infection Hereditary Angioedema Therapeutic Gene Modulation Antisense RNA Familial Amyloid Polyneuropathy Severe And Rare Diseases Familial Chylomicronemia Syndrome Familial Partial Lipodystrophy Homozygous Familial Hypercholesterolemia Myotonic Dystrophy TTR Amyloidosis

Is IONS a Buy, Sell or Hold?

Indicator Bull Case Neutral / Hold Bear Case
50 DMA
200 DMA
ADX Trend
Oversold / Overbought
Relative Strength


Indicator Value
52 Week High 86.08
52 Week Low 39.32
Average Volume 1,006,624
200-Day Moving Average 60.17
50-Day Moving Average 53.53
20-Day Moving Average 46.93
10-Day Moving Average 47.17
Average True Range 3.40
ADX 33.05
+DI 12.92
-DI 19.72
Chandelier Exit (Long, 3 ATRs ) 44.59
Chandelier Exit (Short, 3 ATRs ) 49.53
Upper Bollinger Band 52.68
Lower Bollinger Band 41.17
Percent B (%b) 0.59
BandWidth 24.52
MACD Line -1.51
MACD Signal Line -2.25
MACD Histogram 0.7405
Fundamentals Value
Market Cap 5.97 Billion
Num Shares 124 Million
EPS 0.21
Price-to-Earnings (P/E) Ratio 228.57
Price-to-Sales 13.91
Price-to-Book 31.29
PEG Ratio -7.79
Dividend 0.00
Dividend Yield 0.00%
Pivot Point Level Traditional / Classic Fibonacci Demark Woodie Camarilla
Resistance 4 (R4) 50.54
Resistance 3 (R3) 50.80 50.22 50.11
Resistance 2 (R2) 50.22 49.57 50.09 49.97
Resistance 1 (R1) 49.11 49.18 48.82 48.85 49.83
Pivot Point 48.53 48.53 48.39 48.40 48.53
Support 1 (S1) 47.42 47.88 47.13 47.16 46.17
Support 2 (S2) 46.84 47.49 46.71 46.03
Support 3 (S3) 45.73 46.84 45.89
Support 4 (S4) 45.47