SBIO vs. MMSC ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to First Trust Multi-Manager Small (MMSC)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$37.20

Average Daily Volume

8,661

Number of Holdings *

83

* may have additional holdings in another (foreign) market
MMSC

First Trust Multi-Manager Small

MMSC Description First Trust Multi-Manager Small is an exchange traded fund launched and managed by First Trust Advisors L.P. The fund is co-managed by Driehaus Capital Management LLC and Stephens Investment Management Group. It invests in the public equity markets of global region. The fund invests in stocks of companies operating across diversified sectors. It invests in growth stocks of small cap companies, within the market capitalization range of the Russell 2000 Growth Index. The fund invests in stocks of companies that are deemed socially conscious in their business dealings and directly promote environmental responsibility. The fund employs external research to create its portfolio. First Trust Multi-Manager Small was formed on October 13, 2021 and is domiciled in the United States.

Grade (RS Rating)

Last Trade

$22.20

Average Daily Volume

7,185

Number of Holdings *

181

* may have additional holdings in another (foreign) market
Performance
Period SBIO MMSC
30 Days -5.42% 6.25%
60 Days -4.09% 7.98%
90 Days 0.49% 9.85%
12 Months 48.12% 42.25%
7 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in MMSC Overlap
CRNX C 2.95% 1.41% 1.41%
EWTX C 1.92% 0.24% 0.24%
KRYS C 3.39% 0.16% 0.16%
MRUS F 2.21% 0.35% 0.35%
PTCT B 2.02% 0.13% 0.13%
RNA C 3.29% 0.34% 0.34%
XENE D 2.01% 0.73% 0.73%
SBIO Overweight 76 Positions Relative to MMSC
Symbol Grade Weight
CORT B 3.66%
ACLX C 3.19%
ALKS C 3.15%
IMVT F 2.66%
DNLI D 2.36%
AGIO C 2.05%
VRNA B 1.98%
FOLD F 1.95%
ACAD C 1.89%
VERA C 1.82%
ZLAB C 1.79%
VCEL B 1.73%
PTGX D 1.61%
CGON F 1.57%
IDYA F 1.53%
GERN D 1.48%
MIRM B 1.47%
KROS D 1.4%
LBPH A 1.4%
AKRO B 1.32%
MNKD C 1.26%
IRON B 1.21%
GLPG F 1.19%
TARS C 1.16%
IMCR D 1.07%
CLDX F 1.06%
ARVN F 1.06%
BCRX D 0.99%
XNCR B 0.98%
RCUS F 0.95%
NTLA F 0.94%
SNDX F 0.93%
SPRY C 0.88%
VRDN D 0.84%
KURA F 0.83%
DAWN D 0.82%
AUPH B 0.78%
PHVS C 0.76%
APLT C 0.72%
COGT D 0.69%
ETNB C 0.57%
LQDA F 0.54%
PLRX D 0.53%
PRTA F 0.52%
ERAS C 0.51%
REPL D 0.5%
IRWD F 0.44%
AVXL B 0.42%
ANNX F 0.4%
MLYS F 0.39%
ALT C 0.37%
OLMA F 0.37%
ANAB F 0.36%
FLGT F 0.35%
ALLO F 0.35%
CELC F 0.34%
YMAB F 0.34%
URGN F 0.34%
SVRA F 0.34%
FULC F 0.33%
TBPH B 0.32%
FDMT F 0.31%
GHRS C 0.31%
ARCT F 0.31%
AURA C 0.3%
ALEC F 0.28%
CMPS F 0.23%
ACIU D 0.22%
VNDA C 0.2%
ITOS F 0.19%
STRO F 0.17%
ALDX D 0.17%
ZNTL F 0.17%
ENTA F 0.14%
INZY F 0.12%
HLVX F 0.06%
SBIO Underweight 174 Positions Relative to MMSC
Symbol Grade Weight
AXON A -2.41%
BRBR A -1.67%
CYBR A -1.65%
AAON B -1.39%
VRNS D -1.29%
SGBX F -1.13%
COHR B -1.09%
PLMR A -1.05%
AVAV C -0.99%
PCVX D -0.97%
SFM A -0.97%
FTI A -0.94%
MOD A -0.93%
KTOS B -0.91%
HQY A -0.9%
FRPT A -0.84%
CWAN B -0.84%
GKOS B -0.82%
MANH D -0.82%
NTRA A -0.8%
CW C -0.79%
RBC A -0.78%
RYAN A -0.77%
GWRE A -0.74%
EZPW B -0.72%
EXEL B -0.71%
MNDY C -0.7%
CVNA B -0.68%
LGND C -0.68%
FN C -0.68%
HEI A -0.67%
VSEC C -0.66%
CVLT B -0.66%
KNF B -0.66%
RVLV A -0.65%
ERJ A -0.64%
BFAM D -0.64%
MGNI B -0.64%
SPSC D -0.63%
HALO F -0.62%
SUPN C -0.61%
MGY A -0.6%
FCN F -0.59%
SMTC B -0.59%
CRDO B -0.58%
MMS F -0.57%
PIPR A -0.57%
TTEK F -0.57%
BCPC B -0.56%
FLS B -0.56%
ITRI C -0.55%
POWL C -0.55%
ECPG C -0.55%
MKTX D -0.55%
WULF C -0.54%
ICFI F -0.53%
CR A -0.52%
MTSI B -0.51%
VRT B -0.51%
WING D -0.51%
TMDX F -0.51%
SITE F -0.5%
KNSL B -0.5%
FIX A -0.5%
LTH C -0.5%
SKY A -0.5%
PZZA F -0.49%
UPST B -0.48%
VIRT A -0.48%
ITGR B -0.47%
KMPR A -0.46%
PSN D -0.46%
EVR B -0.45%
STRL A -0.45%
RGEN D -0.45%
WVE C -0.45%
MEDP D -0.44%
TBBK B -0.44%
HUBG A -0.44%
ALSN B -0.43%
CRS B -0.43%
AZEK A -0.43%
TREX C -0.43%
SITM B -0.42%
BROS A -0.42%
WAL B -0.42%
KRNT B -0.41%
NTNX B -0.41%
GLOB B -0.41%
KYMR D -0.41%
RARE F -0.4%
LAD A -0.4%
BOOT C -0.39%
INTA B -0.39%
GMED A -0.38%
ONTO F -0.38%
TECH F -0.38%
SKWD A -0.38%
NUVL C -0.38%
IRTC C -0.37%
RYTM C -0.37%
TENB C -0.37%
FSS B -0.37%
TOST B -0.37%
VERX A -0.36%
RBRK A -0.36%
MOG.A B -0.35%
PRO C -0.35%
S B -0.35%
UEC B -0.35%
HSTM B -0.35%
WIX A -0.34%
LNN B -0.34%
ASO F -0.34%
ITCI C -0.33%
EME A -0.33%
BMI B -0.33%
NEOG F -0.33%
AZTA D -0.32%
ALTR B -0.31%
IBP D -0.31%
ACHC F -0.31%
BLFS C -0.31%
OLLI D -0.31%
RMBS B -0.31%
HCI C -0.3%
FWRG C -0.3%
RXO D -0.3%
SDGR C -0.3%
CIEN C -0.3%
AIT B -0.29%
LRN A -0.29%
MEG F -0.29%
LNTH D -0.29%
SHAK C -0.28%
PSTG D -0.28%
WHD B -0.27%
COMP B -0.27%
ALKT B -0.27%
POWI F -0.27%
AMRC F -0.26%
CGNX D -0.26%
SAIA B -0.26%
BWXT B -0.26%
JBT B -0.26%
GNRC C -0.26%
ROAD B -0.26%
LSCC D -0.25%
AMBA B -0.25%
TNDM D -0.25%
ANF F -0.25%
CHEF A -0.25%
LASR D -0.25%
SLAB F -0.24%
MTH D -0.24%
ESI B -0.24%
QNST B -0.24%
FIVE F -0.23%
PI D -0.23%
BECN B -0.22%
ASPN F -0.2%
BRZE C -0.19%
ICLR D -0.18%
ZETA D -0.17%
MAX F -0.17%
DNUT F -0.16%
AGYS A -0.16%
ENVX F -0.15%
PODD C -0.15%
RXST F -0.14%
OSCR D -0.11%
CELH F -0.1%
CSWI B -0.07%
INSM C -0.06%
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