SBIO vs. GURU ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to Global X Top Guru Holdings Index ETF (GURU)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$38.26

Average Daily Volume

6,572

Number of Holdings *

83

* may have additional holdings in another (foreign) market
GURU

Global X Top Guru Holdings Index ETF

GURU Description The investment seeks investment results that correspond generally to the price and yield performance, before fees and expenses, of the Top Guru Holdings Index ("underlying index"). The fund invests at least 80% of its total assets in the securities of the underlying index and in ADRs based on the securities in the underlying index. The underlying index is comprised of the top U.S. listed equity positions reported on Form 13F by a select group of entities that Structured Solutions AG (the "Index Provider") characterizes as hedge funds. The Adviser uses a "passive" or indexing approach to try to achieve the fund's investment objective. It is non-diversified.

Grade (RS Rating)

Last Trade

$48.91

Average Daily Volume

1,281

Number of Holdings *

60

* may have additional holdings in another (foreign) market
Performance
Period SBIO GURU
30 Days 1.91% 2.48%
60 Days 2.27% 6.44%
90 Days 7.65% 14.02%
12 Months 52.91% 39.99%
2 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in GURU Overlap
FOLD B 2.27% 1.49% 1.49%
PTCT B 2.05% 1.82% 1.82%
SBIO Overweight 81 Positions Relative to GURU
Symbol Grade Weight
RNA C 3.38%
KRYS C 3.33%
CORT B 3.2%
CRNX B 3.04%
ACLX B 3.02%
IMVT F 2.93%
ALKS F 2.88%
DNLI C 2.39%
MRUS C 2.38%
ZLAB B 2.11%
XENE C 2.03%
EWTX B 2.03%
VRNA A 1.83%
PTGX B 1.77%
CGON F 1.67%
AGIO B 1.65%
IDYA F 1.61%
ACAD F 1.57%
GERN C 1.55%
VERA A 1.5%
KROS A 1.41%
VCEL D 1.35%
LBPH A 1.34%
AKRO A 1.3%
MIRM B 1.25%
GLPG F 1.25%
ARVN C 1.22%
CLDX F 1.21%
MNKD A 1.14%
BCRX A 1.1%
SNDX F 1.07%
IMCR F 1.06%
RCUS F 1.04%
NTLA F 1.03%
TARS A 0.97%
VRDN B 0.93%
SPRY B 0.92%
IRON D 0.9%
KURA F 0.89%
COGT B 0.89%
XNCR A 0.87%
DAWN A 0.85%
PHVS A 0.77%
APLT A 0.71%
AUPH A 0.65%
ANAB F 0.59%
PRTA F 0.58%
LQDA C 0.58%
PLRX A 0.56%
ETNB D 0.54%
REPL B 0.53%
ERAS C 0.48%
ANNX B 0.47%
OLMA F 0.46%
MLYS B 0.44%
YMAB A 0.43%
IRWD F 0.4%
CELC D 0.4%
ALLO D 0.38%
SVRA D 0.37%
FLGT C 0.37%
URGN F 0.35%
ARCT F 0.35%
AURA B 0.34%
FULC F 0.34%
ALT D 0.32%
ALEC D 0.3%
CMPS F 0.29%
AVXL A 0.29%
TBPH C 0.28%
FDMT F 0.27%
GHRS D 0.25%
ALDX D 0.21%
ACIU F 0.2%
INZY F 0.19%
STRO D 0.19%
ITOS F 0.19%
ENTA D 0.17%
VNDA D 0.17%
ZNTL D 0.15%
HLVX C 0.06%
SBIO Underweight 58 Positions Relative to GURU
Symbol Grade Weight
CEG B -2.01%
DAL A -1.98%
TPL A -1.91%
NUVL D -1.89%
ORCL B -1.85%
GWRE B -1.85%
FI A -1.78%
BABA B -1.76%
EXPE B -1.76%
MRVL A -1.72%
PWR B -1.68%
NVDA B -1.66%
CPNG B -1.66%
LAD A -1.66%
TSM B -1.65%
WELL A -1.65%
PCG B -1.63%
HD B -1.62%
CMG B -1.6%
JHG A -1.59%
MA B -1.58%
CRM A -1.58%
UTHR A -1.57%
CARR D -1.55%
GRBK D -1.55%
INCY A -1.54%
CYBR C -1.54%
HWM B -1.53%
META B -1.53%
EDR A -1.52%
ROIV D -1.52%
AMZN A -1.52%
LIN C -1.51%
STX D -1.51%
RBLX A -1.5%
AAPL C -1.49%
K A -1.47%
HES B -1.47%
SHW D -1.47%
MSFT D -1.46%
GOOGL A -1.46%
ASH F -1.45%
SPGI D -1.45%
GDDY A -1.44%
CSX F -1.43%
POST D -1.43%
PLNT D -1.43%
UNH C -1.41%
ABG C -1.41%
THC C -1.41%
PLD F -1.4%
CAR C -1.38%
X C -1.37%
ACI C -1.33%
SNOW C -1.31%
HTZ F -1.3%
MDGL A -1.21%
ESTC D -1.04%
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