Smith & Nephew plc develops, manufactures, markets, and sells medical devices in the advanced surgical devices and advanced wound management sectors worldwide. The company's Advanced Surgical Devices segment offers orthopaedic reconstruction implants for hip, knee, and shoulder joints; and ancillary products, such as bone cement and mixing systems used in cemented reconstruction joint surgery. It also provides sports medicine products, which offer surgeons an array of instruments, technologies, and implants to perform minimally invasive surgery of the joints, including knee, hip, and shoulder repair; and orthopaedic trauma fixation products consisting of internal and external devices and other products, including shoulder fixation and orthobiological materials used in the stabilization of fractures and deformity correction procedures. In addition, this segment provides arthroscopy enabling technologies comprising fluid management equipment for surgical access, such as cameras, digital image capture, scopes, light sources, and monitors to assist with visualization inside the joints, as well as offers radio frequency wands, electromechanical and mechanical blades, and hand instruments for removing damaged tissues to healthcare providers. The company's Advanced Wound Management segment offers a range of initial wound bed preparation and full wound closure products. Its products are targeted at chronic wounds associated with the older population, such as pressure sores and venous leg ulcers; and products for the treatment of wounds, such as burns and invasive surgery. The company's principal products include ALLEVYN and DURAFIBER branded wound care products; ACTICOAT branded products for infection management; and negative pressure wound therapy products. Smith & Nephew plc primarily serves medical and surgical service providers. The company was founded in 1856 and is headquartered in London, the United Kingdom.