Gm1 Gangliosidosis is a rare, inherited metabolic disorder caused by a deficiency of the enzyme beta-galactosidase. This enzyme is responsible for breaking down certain fatty substances called gangliosides. When the enzyme is deficient, these gangliosides accumulate in the body, leading to a wide range of neurological and physical symptoms. Symptoms of Gm1 Gangliosidosis can include seizures, developmental delays, muscle weakness, hearing loss, vision problems, and difficulty swallowing.