XBI vs. HRTS ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to Tema Cardiovascular and Metabolic ETF (HRTS)
XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$94.30

Average Daily Volume

8,465,460

Number of Holdings *

128

* may have additional holdings in another (foreign) market
HRTS

Tema Cardiovascular and Metabolic ETF

HRTS Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from products or services related to the treatment of cardiovascular diseases and/or metabolic diseases, as defined by the Centers for Diseases Control and Preventions. The fund advisor generally is expected to consist of more than 15 companies but not more than 100 companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$30.77

Average Daily Volume

14,144

Number of Holdings *

36

* may have additional holdings in another (foreign) market
Performance
Period XBI HRTS
30 Days -4.04% -9.25%
60 Days -7.18% -11.27%
90 Days -7.09% -12.29%
12 Months 29.73% 15.50%
18 Overlapping Holdings
Symbol Grade Weight in XBI Weight in HRTS Overlap
AKRO B 0.43% 1.28% 0.43%
ALNY D 2.38% 4.95% 2.38%
AMGN F 2.28% 5.11% 2.28%
ARWR D 0.54% 1.76% 0.54%
BBIO F 0.87% 3.69% 0.87%
CRNX C 0.84% 4.0% 0.84%
CYTK F 1.79% 3.47% 1.79%
IONS F 1.08% 2.42% 1.08%
KROS D 0.36% 2.1% 0.36%
MDGL B 2.17% 1.46% 1.46%
MIRM B 0.57% 2.6% 0.57%
NTLA F 0.58% 1.66% 0.58%
RARE F 0.69% 1.71% 0.69%
RCKT F 0.28% 1.8% 0.28%
REGN F 1.8% 2.37% 1.8%
VERV F 0.15% 0.64% 0.15%
VKTX F 2.0% 1.14% 1.14%
VRTX D 2.62% 5.64% 2.62%
XBI Overweight 110 Positions Relative to HRTS
Symbol Grade Weight
NTRA A 3.3%
INCY C 3.29%
GILD C 2.9%
UTHR C 2.88%
NBIX C 2.62%
INSM C 2.43%
ABBV F 2.33%
SRPT F 2.28%
BIIB F 2.19%
EXAS D 2.05%
BMRN F 1.98%
BPMC B 1.69%
CRSP D 1.63%
TGTX B 1.62%
MRNA F 1.57%
RVMD C 1.46%
RNA C 1.32%
KRYS C 1.29%
HALO F 1.27%
EXEL B 1.23%
ADMA B 1.23%
ROIV C 1.18%
ALKS C 1.13%
TWST F 0.93%
PCVX D 0.9%
IOVA F 0.88%
APLS F 0.86%
GERN D 0.86%
ACLX C 0.79%
DYN F 0.78%
ACAD C 0.78%
SWTX C 0.77%
AGIO C 0.76%
BEAM D 0.72%
RXRX F 0.66%
PTCT B 0.64%
FOLD F 0.63%
IMVT F 0.62%
RYTM C 0.61%
NUVL C 0.6%
PTGX D 0.58%
VERA C 0.57%
IDYA F 0.53%
VCYT B 0.53%
JANX C 0.51%
SRRK C 0.49%
DVAX C 0.49%
NVAX F 0.47%
ARDX F 0.47%
VCEL B 0.46%
DNLI D 0.46%
KYMR D 0.45%
SNDX F 0.44%
CGON F 0.42%
ARQT B 0.42%
BCRX D 0.42%
CPRX C 0.41%
IRON B 0.34%
MNKD C 0.34%
CLDX F 0.34%
NRIX C 0.33%
SMMT D 0.33%
VRDN D 0.3%
DAWN D 0.28%
MYGN F 0.27%
IRWD F 0.26%
TVTX C 0.26%
CGEM F 0.25%
CDNA D 0.24%
KURA F 0.24%
XNCR B 0.24%
APLT C 0.22%
CDMO A 0.22%
RCUS F 0.2%
VIR D 0.2%
EBS C 0.2%
REPL D 0.18%
HUMA F 0.18%
ALT C 0.18%
SPRY C 0.18%
AVXL B 0.17%
ARCT F 0.17%
ANNX F 0.16%
STOK F 0.16%
ETNB C 0.16%
MDXG B 0.16%
COGT D 0.16%
RLAY F 0.14%
OLMA F 0.13%
IMNM F 0.13%
PRTA F 0.13%
OCGN F 0.12%
ANAB F 0.12%
FDMT F 0.12%
SANA F 0.12%
RGNX D 0.12%
ALLO F 0.11%
CELC F 0.11%
SAGE F 0.11%
CCCC F 0.1%
ERAS C 0.1%
ORIC F 0.09%
FATE F 0.08%
SVRA F 0.08%
ABUS D 0.07%
KALV F 0.07%
SCLX F 0.06%
YMAB F 0.06%
ITOS F 0.06%
ALEC F 0.04%
XBI Underweight 18 Positions Relative to HRTS
Symbol Grade Weight
LLY F -6.44%
BSX A -2.99%
ASND F -2.88%
MDT D -2.79%
DXCM C -2.57%
MREO F -2.49%
MASI B -2.39%
EW C -1.91%
MLYS F -1.89%
PODD C -1.88%
WST C -1.43%
NVS F -1.26%
NARI C -0.97%
EWTX C -0.96%
SLN F -0.91%
TERN F -0.7%
TNYA D -0.43%
RANI F -0.31%
Compare ETFs