HRTS vs. SBIO ETF Comparison

Comparison of Tema Cardiovascular and Metabolic ETF (HRTS) to ALPS Medical Breakthroughs ETF (SBIO)
HRTS

Tema Cardiovascular and Metabolic ETF

HRTS Description

Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from products or services related to the treatment of cardiovascular diseases and/or metabolic diseases, as defined by the Centers for Diseases Control and Preventions. The fund advisor generally is expected to consist of more than 15 companies but not more than 100 companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$33.20

Average Daily Volume

14,638

Number of Holdings *

36

* may have additional holdings in another (foreign) market
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$38.26

Average Daily Volume

6,572

Number of Holdings *

83

* may have additional holdings in another (foreign) market
Performance
Period HRTS SBIO
30 Days -0.75% 1.91%
60 Days -6.06% 2.27%
90 Days -1.75% 7.65%
12 Months 52.91%
7 Overlapping Holdings
Symbol Grade Weight in HRTS Weight in SBIO Overlap
AKRO A 1.19% 1.3% 1.19%
CRNX B 3.79% 3.04% 3.04%
EWTX B 0.99% 2.03% 0.99%
KROS A 1.96% 1.41% 1.41%
MIRM B 2.08% 1.25% 1.25%
MLYS B 2.05% 0.44% 0.44%
NTLA F 2.11% 1.03% 1.03%
HRTS Overweight 29 Positions Relative to SBIO
Symbol Grade Weight
AMGN C 7.87%
LLY F 5.48%
ALNY C 5.47%
VRTX D 4.96%
BBIO D 3.62%
CYTK F 3.25%
MDT B 2.9%
REGN F 2.76%
MREO D 2.68%
MASI A 2.52%
IONS F 2.41%
BSX C 2.28%
RARE D 2.22%
RCKT F 2.07%
ASND F 2.06%
PODD A 2.03%
DXCM C 1.99%
EW D 1.97%
ARWR F 1.58%
NVS D 1.33%
WST B 1.17%
SLN F 1.13%
VKTX A 1.07%
MDGL A 0.95%
NARI A 0.84%
TERN D 0.72%
VERV C 0.64%
TNYA F 0.38%
RANI F 0.32%
HRTS Underweight 76 Positions Relative to SBIO
Symbol Grade Weight
RNA C -3.38%
KRYS C -3.33%
CORT B -3.2%
ACLX B -3.02%
IMVT F -2.93%
ALKS F -2.88%
DNLI C -2.39%
MRUS C -2.38%
FOLD B -2.27%
ZLAB B -2.11%
PTCT B -2.05%
XENE C -2.03%
VRNA A -1.83%
PTGX B -1.77%
CGON F -1.67%
AGIO B -1.65%
IDYA F -1.61%
ACAD F -1.57%
GERN C -1.55%
VERA A -1.5%
VCEL D -1.35%
LBPH A -1.34%
GLPG F -1.25%
ARVN C -1.22%
CLDX F -1.21%
MNKD A -1.14%
BCRX A -1.1%
SNDX F -1.07%
IMCR F -1.06%
RCUS F -1.04%
TARS A -0.97%
VRDN B -0.93%
SPRY B -0.92%
IRON D -0.9%
KURA F -0.89%
COGT B -0.89%
XNCR A -0.87%
DAWN A -0.85%
PHVS A -0.77%
APLT A -0.71%
AUPH A -0.65%
ANAB F -0.59%
PRTA F -0.58%
LQDA C -0.58%
PLRX A -0.56%
ETNB D -0.54%
REPL B -0.53%
ERAS C -0.48%
ANNX B -0.47%
OLMA F -0.46%
YMAB A -0.43%
IRWD F -0.4%
CELC D -0.4%
ALLO D -0.38%
SVRA D -0.37%
FLGT C -0.37%
URGN F -0.35%
ARCT F -0.35%
AURA B -0.34%
FULC F -0.34%
ALT D -0.32%
ALEC D -0.3%
CMPS F -0.29%
AVXL A -0.29%
TBPH C -0.28%
FDMT F -0.27%
GHRS D -0.25%
ALDX D -0.21%
ACIU F -0.2%
INZY F -0.19%
STRO D -0.19%
ITOS F -0.19%
ENTA D -0.17%
VNDA D -0.17%
ZNTL D -0.15%
HLVX C -0.06%
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