HRTS vs. OZEM ETF Comparison

Comparison of Tema Cardiovascular and Metabolic ETF (HRTS) to Roundhill GLP-1 & Weight Loss ETF (OZEM)
HRTS

Tema Cardiovascular and Metabolic ETF

HRTS Description

Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from products or services related to the treatment of cardiovascular diseases and/or metabolic diseases, as defined by the Centers for Diseases Control and Preventions. The fund advisor generally is expected to consist of more than 15 companies but not more than 100 companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$30.77

Average Daily Volume

14,145

Number of Holdings *

36

* may have additional holdings in another (foreign) market
OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.29

Average Daily Volume

37,622

Number of Holdings *

14

* may have additional holdings in another (foreign) market
Performance
Period HRTS OZEM
30 Days -9.25% -10.60%
60 Days -11.27% -11.17%
90 Days -12.29% -12.25%
12 Months 15.50%
5 Overlapping Holdings
Symbol Grade Weight in HRTS Weight in OZEM Overlap
AMGN F 5.11% 3.26% 3.26%
LLY F 6.44% 14.13% 6.44%
REGN F 2.37% 2.4% 2.37%
TERN F 0.7% 1.97% 0.7%
VKTX F 1.14% 3.39% 1.14%
HRTS Overweight 31 Positions Relative to OZEM
Symbol Grade Weight
VRTX D 5.64%
ALNY D 4.95%
CRNX C 4.0%
BBIO F 3.69%
CYTK F 3.47%
BSX A 2.99%
ASND F 2.88%
MDT D 2.79%
MIRM B 2.6%
DXCM C 2.57%
MREO F 2.49%
IONS F 2.42%
MASI B 2.39%
KROS D 2.1%
EW C 1.91%
MLYS F 1.89%
PODD C 1.88%
RCKT F 1.8%
ARWR D 1.76%
RARE F 1.71%
NTLA F 1.66%
MDGL B 1.46%
WST C 1.43%
AKRO B 1.28%
NVS D 1.26%
NARI C 0.97%
EWTX C 0.96%
SLN F 0.91%
VERV F 0.64%
TNYA D 0.43%
RANI F 0.31%
HRTS Underweight 9 Positions Relative to OZEM
Symbol Grade Weight
NVO F -17.04%
ALT C -4.44%
AZN F -3.99%
PFE F -3.07%
SRRK C -2.8%
RYTM C -2.3%
TAK D -2.17%
CORT B -1.77%
OPK C -1.72%
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