HELX vs. MEDX ETF Comparison

Comparison of Franklin Genomic Advancements ETF (HELX) to Horizon Kinetics Medical ETF (MEDX)
HELX

Franklin Genomic Advancements ETF

HELX Description

Seeks capital appreciation by investing in innovative companies related to genomic-based technologies designed to enhance the quality of life. Provides access to companies benefitting from or facilitating the use of new research including DNA sequencing, gene editing and personalized medicine Uses bottom-up fundamental research conducted by dedicated, industry-specific analysts to identify disruptive business models at the right stage for investment Actively managed by a seasoned portfolio management team that is based in Silicon Valley and has a long history of investing in the craft of innovation

Grade (RS Rating)

Last Trade

$29.53

Average Daily Volume

2,580

Number of Holdings *

53

* may have additional holdings in another (foreign) market
MEDX

Horizon Kinetics Medical ETF

MEDX Description The fund is an actively-managed exchange-traded fund ("ETF") that pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets plus any borrowings for investment purposes in common stocks, convertible securities, warrants and other equity securities having the characteristics of common stocks of U.S. and foreign companies engaged in medical research, pharmaceutical and medical technology industries and related technology industries. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$27.37

Average Daily Volume

1,018

Number of Holdings *

32

* may have additional holdings in another (foreign) market
Performance
Period HELX MEDX
30 Days -5.99% -10.09%
60 Days -10.44% -12.50%
90 Days -11.92% -13.78%
12 Months 6.42% -4.11%
9 Overlapping Holdings
Symbol Grade Weight in HELX Weight in MEDX Overlap
ALNY D 1.98% 4.45% 1.98%
AZN F 2.34% 4.86% 2.34%
BEAM D 1.03% 1.51% 1.03%
BMY B 0.36% 6.23% 0.36%
CRSP D 0.5% 2.97% 0.5%
IONS F 2.1% 2.78% 2.1%
LLY F 4.63% 15.83% 4.63%
NTLA F 0.51% 1.3% 0.51%
REGN F 4.3% 3.38% 3.38%
HELX Overweight 44 Positions Relative to MEDX
Symbol Grade Weight
VRTX D 5.94%
KRYS C 4.7%
NTRA A 4.64%
MEDP D 4.07%
TMO F 4.01%
DHR F 3.99%
UTHR C 2.75%
CDNS B 2.34%
CTVA C 2.29%
CRL D 2.23%
BNTX C 2.21%
A D 2.11%
INSM C 2.08%
RVTY F 2.01%
QGEN D 1.96%
BRKR D 1.94%
SRPT F 1.5%
RARE F 1.46%
RCKT F 1.42%
TWST F 1.27%
LGND C 1.27%
ICLR D 1.25%
EXAS D 1.2%
LH B 1.15%
IQV F 1.08%
RGEN D 1.08%
TECH F 1.01%
VYGR F 0.99%
AZTA D 0.95%
NBIX C 0.94%
BBIO F 0.91%
RXRX F 0.69%
MRNA F 0.66%
BIO C 0.59%
VCYT B 0.56%
DVAX C 0.53%
DOCS C 0.51%
CDMO A 0.51%
AVTR F 0.46%
CRNX C 0.25%
BMRN F 0.2%
ARE F 0.15%
SLP D 0.11%
FDMT F 0.1%
HELX Underweight 23 Positions Relative to MEDX
Symbol Grade Weight
ABBV F -7.81%
AMGN F -5.96%
NVS F -5.95%
JNJ C -4.65%
PFE F -4.04%
MRK D -3.96%
ALKS C -3.91%
BIIB F -3.08%
GSK F -2.32%
BCYC F -1.95%
REPL D -0.98%
GALT C -0.89%
HLN C -0.79%
VNDA C -0.79%
LTRN F -0.6%
EDIT F -0.53%
GEHC D -0.48%
TSVT F -0.41%
ALLO F -0.28%
VTRS A -0.27%
PACB F -0.13%
BLUE F -0.08%
MURA D -0.05%
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