Advanced non-small cell lung cancer (NSCLC) is a type of lung cancer that has spread beyond the lungs to other parts of the body. It is the most common type of lung cancer, accounting for about 85% of all cases. Symptoms of advanced NSCLC may include shortness of breath, chest pain, fatigue, and weight loss. Treatment options for advanced NSCLC may include chemotherapy, radiation therapy, targeted therapy, and immunotherapy.