XBI vs. WDNA ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to WisdomTree BioRevolution Fund (WDNA)

XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$96.24

Average Daily Volume

8,531,296

Number of Holdings ^*

128

* may have additional holdings in another (foreign) market

WDNA

WisdomTree BioRevolution Fund

WDNA Description

The investment seeks to track the price and yield performance, before fees and expenses, of the WisdomTree BioRevolution Index (?index?). The fund generally uses a representative sampling strategy to achieve its investment objective, meaning it generally will invest in a sample of the securities in the index whose risk, return and other characteristics resemble the risk, return and other characteristics of the Index as a whole. The index is designed to provide exposure to equity securities of exchange listed companies globally that will be significantly transformed by advancements in genetics and biotechnology. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$15.37

Average Daily Volume

770

Number of Holdings ^*

* may have additional holdings in another (foreign) market

Performance

Period	XBI	WDNA
30 Days	-0.44%	-2.58%
60 Days	-2.97%	-6.57%
90 Days	-5.18%	-8.47%
12 Months	32.40%	2.09%

37 Overlapping Holdings

Symbol	Grade	Weight in XBI	Weight in WDNA	Overlap
ACLX	C	0.79%	0.84%	0.79%
AGIO	C	0.76%	3.0%	0.76%
ALLO	F	0.11%	0.65%	0.11%
ALNY	D	2.38%	1.53%	1.53%
AMGN	D	2.28%	1.33%	1.33%
ARCT	F	0.17%	1.08%	0.17%
ARWR	F	0.54%	0.9%	0.54%
BBIO	F	0.87%	1.59%	0.87%
BEAM	D	0.72%	1.22%	0.72%
BIIB	F	2.19%	0.66%	0.66%
BMRN	D	1.98%	0.73%	0.73%
BPMC	C	1.69%	2.44%	1.69%
CRSP	D	1.63%	1.2%	1.2%
EXAS	D	2.05%	0.88%	0.88%
FATE	F	0.08%	1.09%	0.08%
FOLD	F	0.63%	1.32%	0.63%
GERN	D	0.86%	2.25%	0.86%
GILD	C	2.9%	1.32%	1.32%
IONS	F	1.08%	1.12%	1.08%
IOVA	F	0.88%	1.93%	0.88%
MRNA	F	1.57%	0.35%	0.35%
MYGN	F	0.27%	1.02%	0.27%
NTLA	F	0.58%	0.51%	0.51%
NTRA	B	3.3%	3.06%	3.06%
RARE	D	0.69%	1.4%	0.69%
REGN	F	1.8%	1.17%	1.17%
RGNX	F	0.12%	0.69%	0.12%
RVMD	C	1.46%	0.83%	0.83%
SANA	F	0.12%	0.35%	0.12%
SRPT	D	2.28%	1.36%	1.36%
STOK	F	0.16%	1.29%	0.16%
TWST	D	0.93%	3.24%	0.93%
UTHR	C	2.88%	1.85%	1.85%
VCEL	B	0.46%	2.48%	0.46%
VCYT	B	0.53%	2.12%	0.53%
VERV	F	0.15%	0.56%	0.15%
VRTX	F	2.62%	1.58%	1.58%

XBI Overweight 91 Positions Relative to WDNA

Symbol	Grade	Weight
INCY	C	3.29%
NBIX	C	2.62%
INSM	C	2.43%
ABBV	D	2.33%
MDGL	B	2.17%
VKTX	F	2.0%
CYTK	F	1.79%
TGTX	B	1.62%
RNA	D	1.32%
KRYS	B	1.29%
HALO	F	1.27%
EXEL	B	1.23%
ADMA	B	1.23%
ROIV	C	1.18%
ALKS	B	1.13%
PCVX	D	0.9%
APLS	D	0.86%
CRNX	C	0.84%
DYN	F	0.78%
ACAD	D	0.78%
SWTX	C	0.77%
RXRX	F	0.66%
PTCT	B	0.64%
IMVT	F	0.62%
RYTM	C	0.61%
NUVL	D	0.6%
PTGX	C	0.58%
VERA	B	0.57%
MIRM	B	0.57%
IDYA	F	0.53%
JANX	C	0.51%
SRRK	B	0.49%
DVAX	C	0.49%
NVAX	F	0.47%
ARDX	F	0.47%
DNLI	D	0.46%
KYMR	D	0.45%
SNDX	F	0.44%
AKRO	B	0.43%
CGON	F	0.42%
ARQT	C	0.42%
BCRX	D	0.42%
CPRX	C	0.41%
KROS	D	0.36%
IRON	B	0.34%
MNKD	C	0.34%
CLDX	F	0.34%
NRIX	D	0.33%
SMMT	D	0.33%
VRDN	D	0.3%
RCKT	F	0.28%
DAWN	F	0.28%
IRWD	F	0.26%
TVTX	B	0.26%
CGEM	F	0.25%
CDNA	D	0.24%
KURA	F	0.24%
XNCR	B	0.24%
APLT	B	0.22%
CDMO	B	0.22%
RCUS	F	0.2%
VIR	D	0.2%
EBS	C	0.2%
REPL	B	0.18%
HUMA	F	0.18%
ALT	C	0.18%
SPRY	D	0.18%
AVXL	B	0.17%
ANNX	F	0.16%
ETNB	C	0.16%
MDXG	B	0.16%
COGT	D	0.16%
RLAY	F	0.14%
OLMA	F	0.13%
IMNM	F	0.13%
PRTA	F	0.13%
OCGN	F	0.12%
ANAB	F	0.12%
FDMT	F	0.12%
CELC	F	0.11%
SAGE	F	0.11%
CCCC	F	0.1%
ERAS	C	0.1%
ORIC	F	0.09%
SVRA	D	0.08%
ABUS	D	0.07%
KALV	D	0.07%
SCLX	F	0.06%
YMAB	F	0.06%
ITOS	F	0.06%
ALEC	F	0.04%

XBI Underweight 38 Positions Relative to WDNA

Symbol	Grade	Weight
LLY	F	-2.2%
CTLT	B	-1.42%
DD	D	-1.35%
DHR	F	-1.32%
NVS	D	-1.3%
NEO	C	-1.28%
BMY	B	-1.27%
LH	C	-1.25%
TSN	B	-1.24%
DAR	C	-1.24%
ZTS	D	-1.16%
CTVA	C	-1.13%
TMO	F	-1.13%
QGEN	D	-1.12%
JNJ	D	-1.1%
ILMN	D	-1.08%
RGEN	D	-1.07%
BNTX	D	-1.04%
TECH	D	-1.03%
MRK	F	-1.01%
AZN	D	-1.01%
DOW	F	-0.97%
BIO	D	-0.96%
GMAB	F	-0.91%
SDGR	C	-0.84%
ADM	D	-0.77%
ARGX	A	-0.77%
PFE	D	-0.75%
FMC	D	-0.68%
CRBU	F	-0.59%
EDIT	F	-0.58%
PACB	F	-0.57%
BYND	F	-0.47%
GPRE	F	-0.47%
TXG	F	-0.44%
ORGN	D	-0.43%
CVAC	F	-0.4%
ABSI	F	-0.38%