XBI vs. MNTL ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to Tema Neuroscience and Mental Health ETF (MNTL)
XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$99.27

Average Daily Volume

6,763,174

Number of Holdings *

128

* may have additional holdings in another (foreign) market
MNTL

Tema Neuroscience and Mental Health ETF

MNTL Description Under normal circumstances, the Tema Neuroscience and Mental Health ETF seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in neuroscience and mental health companies. A company is generally considered to be a neuroscience or mental health company that derives at least 50% of revenues from neuroscience or neurology-related diseases, or mental health. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$26.29

Average Daily Volume

121

Number of Holdings *

37

* may have additional holdings in another (foreign) market
Performance
Period XBI MNTL
30 Days 1.20% 0.36%
60 Days -1.95% -3.89%
90 Days 2.92% -0.50%
12 Months 45.66%
21 Overlapping Holdings
Symbol Grade Weight in XBI Weight in MNTL Overlap
ACAD F 0.62% 1.28% 0.62%
ALEC D 0.05% 0.57% 0.05%
ALKS F 1.09% 1.4% 1.09%
ALNY C 2.87% 4.96% 2.87%
BIIB F 2.42% 3.48% 2.42%
CPRX A 0.4% 2.06% 0.4%
CRNX B 0.87% 3.86% 0.87%
DAWN A 0.3% 1.92% 0.3%
DNLI C 0.47% 2.42% 0.47%
DYN F 0.82% 1.3% 0.82%
IMVT F 0.7% 1.49% 0.7%
IONS F 1.17% 2.47% 1.17%
NBIX C 2.43% 3.76% 2.43%
NTLA F 0.78% 1.87% 0.78%
PRTA F 0.16% 0.99% 0.16%
PTCT B 0.66% 1.13% 0.66%
REGN F 2.11% 5.2% 2.11%
RNA C 1.38% 2.08% 1.38%
SRPT D 2.69% 2.14% 2.14%
SRRK B 0.49% 1.15% 0.49%
VRTX D 2.5% 7.9% 2.5%
XBI Overweight 107 Positions Relative to MNTL
Symbol Grade Weight
EXAS A 2.77%
GILD A 2.72%
UTHR A 2.69%
INCY A 2.65%
ABBV A 2.5%
INSM D 2.49%
AMGN C 2.45%
NTRA B 2.42%
VKTX A 2.34%
BMRN F 2.13%
MRNA F 2.02%
CYTK F 1.73%
BPMC C 1.51%
CRSP C 1.5%
HALO B 1.44%
MDGL A 1.38%
RVMD A 1.24%
KRYS C 1.21%
TGTX A 1.2%
ROIV D 1.16%
PCVX C 1.1%
IOVA B 0.98%
EXEL A 0.96%
ADMA B 0.94%
BBIO D 0.91%
GERN C 0.88%
TWST F 0.87%
APLS F 0.84%
RARE D 0.82%
ACLX B 0.75%
FOLD B 0.71%
RXRX F 0.65%
PTGX B 0.64%
BEAM F 0.62%
AGIO B 0.61%
NUVL D 0.61%
SWTX D 0.6%
IDYA F 0.57%
NVAX F 0.57%
ARWR F 0.54%
JANX A 0.52%
ARDX D 0.51%
MIRM B 0.5%
SNDX F 0.49%
KYMR C 0.49%
VERA A 0.48%
RYTM D 0.48%
BCRX A 0.46%
VCYT A 0.45%
DVAX A 0.44%
CGON F 0.43%
AKRO A 0.4%
CLDX F 0.4%
MYGN F 0.38%
KROS A 0.36%
RCKT F 0.35%
VCEL D 0.35%
ARQT D 0.35%
NRIX B 0.35%
SMMT C 0.33%
VRDN B 0.32%
MNKD A 0.31%
CGEM F 0.27%
IRON D 0.26%
TVTX B 0.25%
KURA F 0.24%
CDNA D 0.24%
IRWD F 0.24%
HUMA D 0.22%
APLT A 0.22%
RCUS F 0.22%
ANAB F 0.21%
XNCR A 0.21%
COGT B 0.21%
ANNX B 0.2%
ARCT F 0.2%
SPRY B 0.2%
VIR B 0.2%
REPL B 0.19%
SANA F 0.19%
EBS B 0.19%
VERV C 0.18%
CDMO C 0.18%
RLAY F 0.17%
SAGE F 0.17%
ALT D 0.16%
OLMA F 0.16%
ETNB D 0.15%
STOK C 0.15%
IMNM F 0.15%
CELC D 0.14%
CCCC F 0.13%
ALLO D 0.13%
FDMT F 0.12%
OCGN F 0.11%
RGNX F 0.11%
AVXL A 0.11%
MDXG C 0.1%
FATE F 0.1%
ORIC D 0.09%
SVRA D 0.09%
ERAS C 0.09%
SCLX D 0.08%
YMAB A 0.08%
KALV D 0.08%
ITOS F 0.07%
ABUS D 0.07%
XBI Underweight 16 Positions Relative to MNTL
Symbol Grade Weight
LLY F -5.4%
ARGX A -4.21%
TEVA A -4.01%
SYK A -3.25%
MDT B -3.04%
ITCI A -2.16%
XENE C -2.16%
AXSM C -1.82%
JAZZ D -1.58%
PEN A -1.41%
DXCM C -1.32%
OPCH F -1.27%
ACHC F -1.12%
VYGR C -0.82%
ARVN C -0.47%
QTRX C -0.46%
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