OZEM vs. XBI ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to SPDR S&P Biotech ETF (XBI)
OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.29

Average Daily Volume

37,622

Number of Holdings *

14

* may have additional holdings in another (foreign) market
XBI

SPDR S&P Biotech ETF

XBI Description The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$93.92

Average Daily Volume

8,304,273

Number of Holdings *

128

* may have additional holdings in another (foreign) market
Performance
Period OZEM XBI
30 Days -10.60% -4.43%
60 Days -11.17% -7.55%
90 Days -12.25% -7.46%
12 Months 29.21%
6 Overlapping Holdings
Symbol Grade Weight in OZEM Weight in XBI Overlap
ALT C 4.44% 0.18% 0.18%
AMGN F 3.26% 2.28% 2.28%
REGN F 2.4% 1.8% 1.8%
RYTM C 2.3% 0.61% 0.61%
SRRK C 2.8% 0.49% 0.49%
VKTX F 3.39% 2.0% 2.0%
OZEM Overweight 8 Positions Relative to XBI
Symbol Grade Weight
NVO F 17.04%
LLY F 14.13%
AZN F 3.99%
PFE F 3.07%
TAK D 2.17%
TERN F 1.97%
CORT B 1.77%
OPK C 1.72%
OZEM Underweight 122 Positions Relative to XBI
Symbol Grade Weight
NTRA A -3.3%
INCY C -3.29%
GILD C -2.9%
UTHR C -2.88%
NBIX C -2.62%
VRTX D -2.62%
INSM C -2.43%
ALNY D -2.38%
ABBV F -2.33%
SRPT F -2.28%
BIIB F -2.19%
MDGL B -2.17%
EXAS D -2.05%
BMRN F -1.98%
CYTK F -1.79%
BPMC B -1.69%
CRSP D -1.63%
TGTX B -1.62%
MRNA F -1.57%
RVMD C -1.46%
RNA C -1.32%
KRYS C -1.29%
HALO F -1.27%
EXEL B -1.23%
ADMA B -1.23%
ROIV C -1.18%
ALKS C -1.13%
IONS F -1.08%
TWST F -0.93%
PCVX D -0.9%
IOVA F -0.88%
BBIO F -0.87%
APLS F -0.86%
GERN D -0.86%
CRNX C -0.84%
ACLX C -0.79%
DYN F -0.78%
ACAD C -0.78%
SWTX C -0.77%
AGIO C -0.76%
BEAM D -0.72%
RARE F -0.69%
RXRX F -0.66%
PTCT B -0.64%
FOLD F -0.63%
IMVT F -0.62%
NUVL C -0.6%
NTLA F -0.58%
PTGX D -0.58%
VERA C -0.57%
MIRM B -0.57%
ARWR D -0.54%
IDYA F -0.53%
VCYT B -0.53%
JANX C -0.51%
DVAX C -0.49%
NVAX F -0.47%
ARDX F -0.47%
VCEL A -0.46%
DNLI D -0.46%
KYMR D -0.45%
SNDX F -0.44%
AKRO B -0.43%
CGON F -0.42%
ARQT B -0.42%
BCRX D -0.42%
CPRX C -0.41%
KROS D -0.36%
IRON B -0.34%
MNKD C -0.34%
CLDX F -0.34%
NRIX C -0.33%
SMMT D -0.33%
VRDN D -0.3%
RCKT F -0.28%
DAWN D -0.28%
MYGN F -0.27%
IRWD F -0.26%
TVTX B -0.26%
CGEM F -0.25%
CDNA D -0.24%
KURA F -0.24%
XNCR B -0.24%
APLT C -0.22%
CDMO A -0.22%
RCUS F -0.2%
VIR D -0.2%
EBS C -0.2%
REPL D -0.18%
HUMA F -0.18%
SPRY C -0.18%
AVXL B -0.17%
ARCT F -0.17%
ANNX F -0.16%
STOK F -0.16%
ETNB C -0.16%
MDXG B -0.16%
COGT D -0.16%
VERV F -0.15%
RLAY F -0.14%
OLMA F -0.13%
IMNM F -0.13%
PRTA F -0.13%
OCGN F -0.12%
ANAB F -0.12%
FDMT F -0.12%
SANA F -0.12%
RGNX D -0.12%
ALLO F -0.11%
CELC F -0.11%
SAGE F -0.11%
CCCC F -0.1%
ERAS C -0.1%
ORIC F -0.09%
FATE F -0.08%
SVRA F -0.08%
ABUS D -0.07%
KALV F -0.07%
SCLX F -0.06%
YMAB F -0.06%
ITOS F -0.06%
ALEC F -0.04%
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