OZEM vs. MEDX ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to Horizon Kinetics Medical ETF (MEDX)

OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$26.27

Average Daily Volume

82,294

Number of Holdings ^*

7

* may have additional holdings in another (foreign) market

MEDX

Horizon Kinetics Medical ETF

MEDX Description

The fund is an actively-managed exchange-traded fund ("ETF") that pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets plus any borrowings for investment purposes in common stocks, convertible securities, warrants and other equity securities having the characteristics of common stocks of U.S. and foreign companies engaged in medical research, pharmaceutical and medical technology industries and related technology industries. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$29.38

Average Daily Volume

523

Number of Holdings ^*

10

* may have additional holdings in another (foreign) market

Performance

Period	OZEM	MEDX
30 Days	4.45%	1.26%
60 Days		6.88%
90 Days		-0.31%
12 Months		-5.29%

2 Overlapping Holdings

	Symbol	Grade	Weight in OZEM	Weight in MEDX	Overlap
	AMGN	B	4.2%	6.05%	4.2%
	LLY	B	21.39%	16.22%	16.22%

OZEM Overweight 5 Positions Relative to MEDX

	Symbol	Grade	Weight
	NVO	A	20.52%
	ALT	F	3.97%
	TERN	C	3.32%
	VKTX	D	3.27%
	GPCR	C	3.14%

OZEM Underweight 8 Positions Relative to MEDX

	Symbol	Grade	Weight
	ABBV	B	-7.29%
	NVS	A	-5.83%
	AZN	B	-5.73%
	MRK	A	-4.96%
	JNJ	C	-4.41%
	PFE	C	-4.37%
	BMY	D	-4.29%
	REGN	A	-4.15%

OZEM: Top Represented Industries & Keywords

Industries: Biotechnology Drug Manufacturers - Major

Keywords: Obesity Biopharmaceutical Diabetes Medicine Pharmaceutical Products Anti Diabetic Drugs Glucagon Growth Hormone Hepatitis Inflammation Life Sciences Neuroscience Non Alcoholic Fatty Liver Disease Peptide Hormones Pulmonary Arterial Hypertension S&P 500 Steatohepatitis Wholesale Distributor Alcohol Alzheimer's Disease

MEDX: Top Represented Industries & Keywords

Industries: Drug Manufacturers - Major Biotechnology

Keywords: S&P 500 Pharmaceutical Products Depressive Disorder Neuroscience Animal Health Hypertension Infectious Diseases Inflammation Ophthalmology Antibiotics Biopharmaceutical Biotechnology Cholesterol Clinic Diabetes Dow Jones Component Drugs Infection Major Depressive Disorder Medication