MEDX vs. OZEM ETF Comparison

Comparison of Horizon Kinetics Medical ETF (MEDX) to Roundhill GLP-1 & Weight Loss ETF (OZEM)
MEDX

Horizon Kinetics Medical ETF

MEDX Description

The fund is an actively-managed exchange-traded fund ("ETF") that pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets plus any borrowings for investment purposes in common stocks, convertible securities, warrants and other equity securities having the characteristics of common stocks of U.S. and foreign companies engaged in medical research, pharmaceutical and medical technology industries and related technology industries. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$29.27

Average Daily Volume

512

Number of Holdings *

32

* may have additional holdings in another (foreign) market
OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$27.32

Average Daily Volume

31,803

Number of Holdings *

14

* may have additional holdings in another (foreign) market
Performance
Period MEDX OZEM
30 Days -4.20% -0.27%
60 Days -8.31% -5.30%
90 Days -4.39% 3.02%
12 Months 4.75%
5 Overlapping Holdings
Symbol Grade Weight in MEDX Weight in OZEM Overlap
AMGN C 6.01% 3.25% 3.25%
AZN F 5.15% 4.28% 4.28%
LLY F 16.14% 15.52% 15.52%
PFE D 4.19% 3.15% 3.15%
REGN F 3.77% 2.61% 2.61%
MEDX Overweight 27 Positions Relative to OZEM
Symbol Grade Weight
ABBV A 8.78%
NVS D 5.98%
BMY A 5.3%
JNJ D 4.65%
ALNY C 4.6%
MRK F 3.99%
ALKS F 3.44%
BIIB F 3.21%
CRSP C 2.87%
IONS F 2.78%
GSK F 2.36%
BCYC D 1.96%
BEAM F 1.22%
NTLA F 1.17%
REPL B 0.99%
HLN D 0.78%
GALT F 0.77%
VNDA D 0.67%
EDIT F 0.54%
LTRN F 0.53%
GEHC D 0.48%
TSVT D 0.45%
ALLO D 0.29%
VTRS B 0.24%
PACB C 0.14%
BLUE F 0.1%
MURA D 0.05%
MEDX Underweight 9 Positions Relative to OZEM
Symbol Grade Weight
NVO F -17.47%
VKTX A -3.69%
ALT D -3.69%
SRRK B -2.62%
TERN D -2.14%
TAK C -1.96%
RYTM D -1.7%
CORT B -1.43%
OPK C -1.35%
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