HELX vs. XBI ETF Comparison

Comparison of Franklin Genomic Advancements ETF (HELX) to SPDR S&P Biotech ETF (XBI)
HELX

Franklin Genomic Advancements ETF

HELX Description

Seeks capital appreciation by investing in innovative companies related to genomic-based technologies designed to enhance the quality of life. Provides access to companies benefitting from or facilitating the use of new research including DNA sequencing, gene editing and personalized medicine Uses bottom-up fundamental research conducted by dedicated, industry-specific analysts to identify disruptive business models at the right stage for investment Actively managed by a seasoned portfolio management team that is based in Silicon Valley and has a long history of investing in the craft of innovation

Grade (RS Rating)

Last Trade

$29.53

Average Daily Volume

2,580

Number of Holdings *

53

* may have additional holdings in another (foreign) market
XBI

SPDR S&P Biotech ETF

XBI Description The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$95.14

Average Daily Volume

8,465,460

Number of Holdings *

128

* may have additional holdings in another (foreign) market
Performance
Period HELX XBI
30 Days -5.99% -4.04%
60 Days -10.44% -7.18%
90 Days -11.92% -7.09%
12 Months 6.42% 29.73%
26 Overlapping Holdings
Symbol Grade Weight in HELX Weight in XBI Overlap
ALNY D 1.98% 2.38% 1.98%
BBIO F 0.91% 0.87% 0.87%
BEAM D 1.03% 0.72% 0.72%
BMRN F 0.2% 1.98% 0.2%
CDMO A 0.51% 0.22% 0.22%
CRNX C 0.25% 0.84% 0.25%
CRSP D 0.5% 1.63% 0.5%
DVAX C 0.53% 0.49% 0.49%
EXAS D 1.2% 2.05% 1.2%
FDMT F 0.1% 0.12% 0.1%
INSM C 2.08% 2.43% 2.08%
IONS F 2.1% 1.08% 1.08%
KRYS C 4.7% 1.29% 1.29%
MRNA F 0.66% 1.57% 0.66%
NBIX C 0.94% 2.62% 0.94%
NTLA F 0.51% 0.58% 0.51%
NTRA A 4.64% 3.3% 3.3%
RARE F 1.46% 0.69% 0.69%
RCKT F 1.42% 0.28% 0.28%
REGN F 4.3% 1.8% 1.8%
RXRX F 0.69% 0.66% 0.66%
SRPT F 1.5% 2.28% 1.5%
TWST F 1.27% 0.93% 0.93%
UTHR C 2.75% 2.88% 2.75%
VCYT B 0.56% 0.53% 0.53%
VRTX D 5.94% 2.62% 2.62%
HELX Overweight 27 Positions Relative to XBI
Symbol Grade Weight
LLY F 4.63%
MEDP D 4.07%
TMO F 4.01%
DHR F 3.99%
AZN F 2.34%
CDNS B 2.34%
CTVA C 2.29%
CRL D 2.23%
BNTX C 2.21%
A D 2.11%
RVTY F 2.01%
QGEN D 1.96%
BRKR D 1.94%
LGND C 1.27%
ICLR D 1.25%
LH B 1.15%
IQV F 1.08%
RGEN D 1.08%
TECH F 1.01%
VYGR F 0.99%
AZTA D 0.95%
BIO C 0.59%
DOCS C 0.51%
AVTR F 0.46%
BMY B 0.36%
ARE F 0.15%
SLP D 0.11%
HELX Underweight 102 Positions Relative to XBI
Symbol Grade Weight
INCY C -3.29%
GILD C -2.9%
ABBV F -2.33%
AMGN F -2.28%
BIIB F -2.19%
MDGL B -2.17%
VKTX F -2.0%
CYTK F -1.79%
BPMC B -1.69%
TGTX B -1.62%
RVMD C -1.46%
RNA C -1.32%
HALO F -1.27%
EXEL B -1.23%
ADMA B -1.23%
ROIV C -1.18%
ALKS C -1.13%
PCVX D -0.9%
IOVA F -0.88%
APLS F -0.86%
GERN D -0.86%
ACLX C -0.79%
DYN F -0.78%
ACAD C -0.78%
SWTX C -0.77%
AGIO C -0.76%
PTCT B -0.64%
FOLD F -0.63%
IMVT F -0.62%
RYTM C -0.61%
NUVL C -0.6%
PTGX D -0.58%
VERA C -0.57%
MIRM B -0.57%
ARWR D -0.54%
IDYA F -0.53%
JANX C -0.51%
SRRK C -0.49%
NVAX F -0.47%
ARDX F -0.47%
VCEL B -0.46%
DNLI D -0.46%
KYMR D -0.45%
SNDX F -0.44%
AKRO B -0.43%
CGON F -0.42%
ARQT B -0.42%
BCRX D -0.42%
CPRX C -0.41%
KROS D -0.36%
IRON B -0.34%
MNKD C -0.34%
CLDX F -0.34%
NRIX C -0.33%
SMMT D -0.33%
VRDN D -0.3%
DAWN D -0.28%
MYGN F -0.27%
IRWD F -0.26%
TVTX C -0.26%
CGEM F -0.25%
CDNA D -0.24%
KURA F -0.24%
XNCR B -0.24%
APLT C -0.22%
RCUS F -0.2%
VIR D -0.2%
EBS C -0.2%
REPL D -0.18%
HUMA F -0.18%
ALT C -0.18%
SPRY C -0.18%
AVXL B -0.17%
ARCT F -0.17%
ANNX F -0.16%
STOK F -0.16%
ETNB C -0.16%
MDXG B -0.16%
COGT D -0.16%
VERV F -0.15%
RLAY F -0.14%
OLMA F -0.13%
IMNM F -0.13%
PRTA F -0.13%
OCGN F -0.12%
ANAB F -0.12%
SANA F -0.12%
RGNX D -0.12%
ALLO F -0.11%
CELC F -0.11%
SAGE F -0.11%
CCCC F -0.1%
ERAS C -0.1%
ORIC F -0.09%
FATE F -0.08%
SVRA F -0.08%
ABUS D -0.07%
KALV F -0.07%
SCLX F -0.06%
YMAB F -0.06%
ITOS F -0.06%
ALEC F -0.04%
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