HELX vs. BTEC ETF Comparison

Comparison of Franklin Genomic Advancements ETF (HELX) to Principal Healthcare Innovators Index ETF (BTEC)

HELX

Franklin Genomic Advancements ETF

HELX Description

Seeks capital appreciation by investing in innovative companies related to genomic-based technologies designed to enhance the quality of life. Provides access to companies benefitting from or facilitating the use of new research including DNA sequencing, gene editing and personalized medicine Uses bottom-up fundamental research conducted by dedicated, industry-specific analysts to identify disruptive business models at the right stage for investment Actively managed by a seasoned portfolio management team that is based in Silicon Valley and has a long history of investing in the craft of innovation

Grade (RS Rating)

Last Trade

$30.95

Average Daily Volume

730

Number of Holdings ^*

* may have additional holdings in another (foreign) market

BTEC

Principal Healthcare Innovators Index ETF

BTEC Description

The investment seeks to provide investment results that closely correspond, before expenses, to the performance of the Nasdaq Healthcare Innovators Index (the "index"). Under normal circumstances, the fund invests at least 80% of its net assets, plus any borrowings for investment purposes, in equity securities of companies that compose the index at the time of purchase. The index uses a quantitative model designed to identify equity securities in the Nasdaq US Benchmark Index (including growth and value stock) that are small and medium capitalization U.S. healthcare companies.

Grade (RS Rating)

Last Trade

$36.90

Average Daily Volume

6,133

Number of Holdings ^*

245

* may have additional holdings in another (foreign) market

Performance

Period	HELX	BTEC
30 Days	-3.44%	0.00%
60 Days	-4.72%	-5.02%
90 Days	2.90%	2.10%
12 Months	2.29%	2.59%

20 Overlapping Holdings

Symbol	Grade	Weight in HELX	Weight in BTEC	Overlap
ALNY	D	1.32%	3.16%	1.32%
AZTA	D	1.08%	0.64%	0.64%
BBIO	F	0.57%	1.09%	0.57%
BEAM	F	0.62%	0.41%	0.41%
CDMO	B	0.55%	0.14%	0.14%
EXAS	F	1.96%	2.31%	1.96%
FDMT	D	1.35%	0.3%	0.3%
INSM	D	0.75%	0.82%	0.75%
IONS	F	2.33%	1.34%	1.34%
MRNA	B	2.08%	3.7%	2.08%
NTLA	F	1.23%	0.49%	0.49%
NTRA	A	2.96%	2.39%	2.39%
RARE	D	1.0%	0.77%	0.77%
RCKT	D	2.11%	0.45%	0.45%
RXRX	F	0.36%	0.41%	0.36%
SRPT	B	1.54%	2.58%	1.54%
TWST	B	0.72%	0.41%	0.41%
TXG	F	0.1%	0.6%	0.1%
VCYT	D	0.15%	0.34%	0.15%
VYGR	D	1.11%	0.12%	0.12%

HELX Overweight 34 Positions Relative to BTEC

Symbol	Grade	Weight
MEDP	D	7.98%
TMO	C	4.91%
VRTX	D	4.78%
REGN	B	4.55%
DHR	C	4.25%
LLY	D	4.24%
KRYS	D	4.09%
BRKR	F	3.2%
AZN	A	2.55%
CRL	D	2.49%
CDNS	D	2.22%
CTVA	A	2.22%
A	C	2.21%
QGEN	C	1.91%
BNTX	D	1.72%
ICLR	D	1.57%
IQV	D	1.21%
RGEN	D	1.05%
LH	F	0.99%
TECH	C	0.87%
NBIX	A	0.81%
CRSP	F	0.8%
BMY	F	0.73%
BIO	D	0.64%
LGND	D	0.61%
AVTR	C	0.54%
SDGR	F	0.51%
UTHR	A	0.5%
DVAX	D	0.49%
SLP	B	0.43%
ARE	D	0.31%
DOCS	F	0.28%
FTRE	C	0.18%
OLK	D	0.12%

HELX Underweight 225 Positions Relative to BTEC

Symbol	Grade	Weight
ILMN	F	-2.84%
CTLT	C	-2.15%
VKTX	C	-1.75%
CERE	A	-1.64%
INSP	B	-1.58%
PCVX	D	-1.48%
ITCI	C	-1.45%
ELAN	D	-1.41%
CYTK	D	-1.41%
BPMC	A	-1.4%
RVMD	A	-1.38%
APLS	F	-1.22%
GKOS	A	-1.11%
ALPN	A	-0.93%
MDGL	D	-0.92%
NUVL	D	-0.91%
IMVT	F	-0.9%
TMDX	A	-0.9%
CRNX	A	-0.79%
IOVA	D	-0.77%
AXSM	C	-0.76%
IRTC	C	-0.74%
JANX	A	-0.72%
PRCT	A	-0.69%
SWTX	D	-0.69%
FOLD	F	-0.67%
IDYA	D	-0.67%
ARWR	F	-0.65%
ENOV	F	-0.62%
SMMT	C	-0.62%
ACLX	D	-0.61%
CLDX	C	-0.58%
PTCT	B	-0.57%
TGTX	C	-0.56%
RYTM	C	-0.54%
VERA	C	-0.53%
TNDM	A	-0.53%
NARI	F	-0.53%
ICUI	F	-0.52%
VCEL	C	-0.51%
DNLI	F	-0.51%
KYMR	D	-0.49%
RXST	A	-0.49%
SANA	C	-0.48%
ARVN	D	-0.48%
GERN	B	-0.48%
DYN	D	-0.47%
DCPH	A	-0.47%
KROS	D	-0.45%
RNA	A	-0.45%
AGIO	A	-0.44%
ATEC	D	-0.41%
SNDX	D	-0.41%
EWTX	B	-0.4%
MYGN	D	-0.39%
ARDX	C	-0.36%
INBX	D	-0.36%
ADMA	A	-0.35%
DAWN	A	-0.35%
KURA	D	-0.35%
PTGX	D	-0.34%
NVCR	D	-0.34%
XNCR	C	-0.33%
RCUS	F	-0.32%
MORF	F	-0.32%
AKRO	F	-0.31%
TARS	C	-0.3%
CGEM	A	-0.29%
MIRM	D	-0.28%
VIR	C	-0.28%
SRRK	C	-0.27%
MRVI	C	-0.27%
PRTA	F	-0.27%
TYRA	C	-0.24%
ATRC	F	-0.24%
MGNX	D	-0.23%
SAVA	B	-0.23%
LQDA	D	-0.23%
ARQT	D	-0.23%
EYPT	D	-0.23%
ALXO	B	-0.22%
SPRY	C	-0.22%
BCRX	F	-0.22%
AVNS	D	-0.22%
RLAY	F	-0.22%
VRDN	F	-0.21%
ELVN	B	-0.21%
CTKB	F	-0.2%
EOLS	D	-0.2%
BLFS	B	-0.2%
OCUL	D	-0.2%
CYRX	D	-0.2%
AUPH	F	-0.19%
KIDS	B	-0.19%
YMAB	C	-0.19%
COGT	C	-0.19%
KNSA	C	-0.19%
LBPH	B	-0.19%
FNA	D	-0.19%
PLRX	F	-0.19%
RGNX	F	-0.19%
ETNB	F	-0.19%
WVE	C	-0.18%
ANAB	B	-0.18%
SILK	B	-0.18%
SAGE	F	-0.18%
ZNTL	F	-0.18%
NVAX	D	-0.17%
HLVX	D	-0.17%
ARCT	F	-0.17%
SIGA	A	-0.17%
NUVB	B	-0.17%
LYEL	C	-0.16%
TMCI	F	-0.16%
SVRA	D	-0.16%
PRME	F	-0.16%
IRON	F	-0.16%
MLYS	D	-0.16%
PHAT	C	-0.15%
CABA	F	-0.15%
HUMA	B	-0.15%
SIBN	F	-0.15%
ORIC	D	-0.15%
NRIX	D	-0.15%
QTRX	F	-0.15%
SRDX	C	-0.14%
KALV	D	-0.14%
OABI	D	-0.14%
AVTE	D	-0.14%
OLMA	F	-0.14%
CDNA	C	-0.13%
PEPG	C	-0.13%
URGN	F	-0.13%
OFIX	F	-0.13%
LRMR	D	-0.13%
ABUS	D	-0.13%
NKTX	D	-0.13%
ALEC	F	-0.13%
THRD	B	-0.13%
ANIK	A	-0.12%
ZIMV	D	-0.12%
EDIT	F	-0.12%
PLSE	D	-0.12%
TVTX	F	-0.12%
TRDA	D	-0.12%
ALLO	F	-0.12%
TBPH	C	-0.12%
HRTX	D	-0.11%
MRSN	D	-0.11%
NVRO	F	-0.11%
REPL	F	-0.11%
LXRX	D	-0.11%
AURA	D	-0.11%
ITOS	C	-0.11%
PACB	F	-0.11%
BMEA	F	-0.11%
CELC	D	-0.11%
VERV	F	-0.11%
ADPT	F	-0.11%
CRMD	B	-0.1%
ERAS	D	-0.1%
PGEN	D	-0.1%
ALT	D	-0.1%
FATE	D	-0.1%
TNYA	D	-0.1%
HROW	F	-0.1%
RVNC	F	-0.1%
LUNG	D	-0.1%
AVXL	F	-0.09%
VTYX	F	-0.09%
ALDX	C	-0.09%
CRBU	F	-0.09%
MGTX	F	-0.09%
CERS	F	-0.09%
IGMS	C	-0.09%
TERN	F	-0.09%
ANNX	D	-0.09%
MCRB	D	-0.08%
CDXS	C	-0.08%
CHRS	F	-0.08%
INZY	D	-0.08%
XERS	F	-0.08%
TSVT	D	-0.08%
OMER	C	-0.08%
ANGO	C	-0.08%
PSTX	D	-0.08%
ATNM	C	-0.08%
ENTA	C	-0.08%
RAPT	F	-0.08%
AKYA	F	-0.07%
OM	D	-0.07%
QSI	C	-0.07%
STRO	F	-0.07%
EBS	C	-0.07%
AXGN	F	-0.07%
MACK	B	-0.07%
FENC	D	-0.07%
BLUE	F	-0.06%
BCAB	C	-0.06%
BFLY	F	-0.06%
INGN	D	-0.06%
XFOR	D	-0.06%
KOD	D	-0.06%
CUTR	D	-0.06%
SCPH	F	-0.06%
RCEL	F	-0.06%
RIGL	D	-0.06%
ALLK	F	-0.05%
KPTI	F	-0.05%
ACRS	D	-0.05%
ARAY	F	-0.05%
CVRX	F	-0.05%
PDSB	F	-0.05%
PMVP	D	-0.05%
OMGA	F	-0.05%
MURA	F	-0.04%
EYEN	F	-0.04%
FGEN	F	-0.04%
ACET	F	-0.04%
SGMO	F	-0.04%
BTAI	F	-0.04%
ATRA	F	-0.04%
GRTS	F	-0.03%
GNLX	F	-0.03%
MRNS	F	-0.02%