Antibody Stocks List

Related ETFs - A few ETFs which own one or more of the above listed Antibody stocks.

Antibody Stocks Recent News

Date Stock Title
Jul 26 TECH Qualcomm Analyst Predicts 34% Upside: 'Share Price Pullback Offers Entry Point'
Jul 26 TECH Tesla Stock Approaches Golden Cross: Is EV Stock Ready To Accelerate?
Jul 26 TECH Microsoft's AI Play Is Silver Lining In Cloudy Quarter: JPMorgan
Jul 26 TECH Tesla Introduces New $120 Detailing Kit For All Of Its Lineup But Cybertruck
Jul 26 TECH Warren Buffett's Early Hustles Shaped His Legendary Career, How The Legendary Investor Went From Paper Routes to Billions
Jul 26 TECH Elon Musk's X Shares Your Posts On His Social Media Platform With Grok For Training: Here's How You Can Disable It
Jul 26 TECH Amazon 'Relatively Insulated' In Retail Segment, Analysts Bullish About Growth In AWS: AI Contribution To Watch Out For
Jul 26 TECH Tesla Says Using Wet Cloth On Supercharger Cables Does Not Increase Charging Speeds, Warns Customers Of 'Risk Of Overheating Or Damage'
Jul 26 TECH Elon Musk's SpaceX To Resume Launch Operations Two Weeks After Mishap Involving 20 Starlink Satellites
Jul 26 TECH Fortnite Is Coming Back To Apple's iPhones, Including Alternative App Stores, But There's A Catch
Jul 26 TECH Elon Musk And Stephen King Entangle Again On X: This Time Horror King Challenges Techno King To A Joke-Off
Jul 26 TECH Visa Leverages AI To Prevent $40B In Fraud: How Machine Learning Is Combatting The Surge In Cybercrime And AI-Driven Scams
Jul 26 TECH CrowdStrike CEO George Kurtz Announces Over 97% Of Windows Sensors Back Online After Global Outage
Jul 26 TECH Trump VP Choice JD Vance Is A Tech-Bro Pick, Says Paul Krugman — Same People Last Year Were Infatuated With Robert Kennedy Jr.
Jul 25 TECH Apple Vision Pro Launches New Lake-Setting Environment For Digital Crown VR
Jul 25 TECH Serve Robotics Stock Continues To Soar: What's Going On?
Jul 25 TECH Nasdaq 100 Falls To 7-Week Lows, Marks Worst 2-Day Drop In Nearly 2 Years As Tech Rout Rages On
Jul 25 ZYME Zymeworks names Leone Patterson as chief business and financial officer
Jul 25 ZYME Zymeworks Appoints Leone Patterson as Chief Business and Financial Officer
Jul 25 TECH Nasdaq Q2 Earnings: Revenue Surge, Financial Tech and Index Segments Show Strong Growth
Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen, via the Fab's variable region. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (similarly, analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize its target directly (for example, by inhibiting a part of a microbe that is essential for its invasion and survival). Depending on the antigen, the binding may impede the biological process causing the disease or may activate macrophages to destroy the foreign substance. The ability of an antibody to communicate with the other components of the immune system is mediated via its Fc region (located at the base of the "Y"), which contains a conserved glycosylation site involved in these interactions. The production of antibodies is the main function of the humoral immune system.Antibodies are secreted by B cells of the adaptive immune system, mostly by differentiated B cells called plasma cells. Antibodies can occur in two physical forms, a soluble form that is secreted from the cell to be free in the blood plasma, and a membrane-bound form that is attached to the surface of a B cell and is referred to as the B-cell receptor (BCR). The BCR is found only on the surface of B cells and facilitates the activation of these cells and their subsequent differentiation into either antibody factories called plasma cells or memory B cells that will survive in the body and remember that same antigen so the B cells can respond faster upon future exposure. In most cases, interaction of the B cell with a T helper cell is necessary to produce full activation of the B cell and, therefore, antibody generation following antigen binding. Soluble antibodies are released into the blood and tissue fluids, as well as many secretions to continue to survey for invading microorganisms.
Antibodies are glycoproteins belonging to the immunoglobulin superfamily. They constitute most of the gamma globulin fraction of the blood proteins. They are typically made of basic structural units—each with two large heavy chains and two small light chains. There are several different types of antibody heavy chains that define the five different types of crystallisable fragments (Fc) that may be attached to the antigen-binding fragments. The five different types of Fc regions allow antibodies to be grouped into five isotypes. Each Fc region of a particular antibody isotype is able to bind to its specific Fc Receptor (except for IgD, which is essentially the BCR), thus allowing the antigen-antibody complex to mediate different roles depending on which FcR it binds. The ability of an antibody to bind to its corresponding FcR is further modulated by the structure of the glycan(s) present at conserved sites within its Fc region. The ability of antibodies to bind to FcRs helps to direct the appropriate immune response for each different type of foreign object they encounter. For example, IgE is responsible for an allergic response consisting of mast cell degranulation and histamine release. IgE's Fab paratope binds to allergic antigen, for example house dust mite particles, while its Fc region binds to Fc receptor ε. The allergen-IgE-FcRε interaction mediates allergic signal transduction to induce conditions such as asthma.Though the general structure of all antibodies is very similar, a small region at the tip of the protein is extremely variable, allowing millions of antibodies with slightly different tip structures, or antigen-binding sites, to exist. This region is known as the hypervariable region. Each of these variants can bind to a different antigen. This enormous diversity of antibody paratopes on the antigen-binding fragments allows the immune system to recognize an equally wide variety of antigens. The large and diverse population of antibody paratope is generated by random recombination events of a set of gene segments that encode different antigen-binding sites (or paratopes), followed by random mutations in this area of the antibody gene, which create further diversity. This recombinational process that produces clonal antibody paratope diversity is called V(D)J or VJ recombination. Basically, the antibody paratope is polygenic, made up of three genes, V, D, and J. Each paratope locus is also polymorphic, such that during antibody production, one allele of V, one of D, and one of J is chosen. These gene segments are then joined together using random genetic recombination to produce the paratope. The regions where the genes are randomly recombined together is the hyper variable region used to recognise different antigens on a clonal basis.
Antibody genes also re-organize in a process called class switching that changes the one type of heavy chain Fc fragment to another, creating a different isotype of the antibody that retains the antigen-specific variable region. This allows a single antibody to be used by different types of Fc receptors, expressed on different parts of the immune system.

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