CD47 Stocks List
Symbol | Grade | Name | Weight | |
---|---|---|---|---|
BBC | C | Virtus LifeSci Biotech Clinical Trials ETF | 0.99 | |
ISMD | C | Inspire Small/Mid Cap Impact ETF | 0.3 | |
BTEC | C | Principal Healthcare Innovators Index ETF | 0.17 | |
AFSM | C | Active Factor Small Cap ETF | 0.14 | |
IWC | C | iShares Microcap ETF | 0.11 |
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- CD47
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers, and more recently, for the treatment of pulmonary fibrosis.CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. CD47 is ubiquitously expressed in human cells and has been found to be overexpressed in many different tumor cells. Expression in equine cutaneous tumors has been reported as well.
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