XBI vs. IBB ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to iShares Nasdaq Biotechnology Index Fund (IBB)

XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$94.30

Average Daily Volume

8,465,460

Number of Holdings ^*

128

* may have additional holdings in another (foreign) market

IBB

iShares Nasdaq Biotechnology Index Fund

IBB Description

The investment seeks to track the investment results of an index composed of biotechnology and pharmaceutical equities listed on the NASDAQ. The fund generally invests at least 90% of its assets in securities of the underlying index and in depositary receipts representing securities of the underlying index. The underlying index contains securities of NASDAQÂ® listed companies that are classified according to the Industry Classification Benchmark as either biotechnology or pharmaceuticals and that also meet other eligibility criteria determined by The NASDAQ OMX Group, Inc. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$136.10

Average Daily Volume

1,176,846

Number of Holdings ^*

184

* may have additional holdings in another (foreign) market

Performance

Period	XBI	IBB
30 Days	-4.04%	-5.49%
60 Days	-7.18%	-8.03%
90 Days	-7.09%	-8.01%
12 Months	29.73%	14.75%

106 Overlapping Holdings

Symbol	Grade	Weight in XBI	Weight in IBB	Overlap
ABUS	D	0.07%	0.05%	0.05%
ACAD	C	0.78%	0.29%	0.29%
ACLX	C	0.79%	0.39%	0.39%
ADMA	B	1.23%	0.48%	0.48%
AGIO	C	0.76%	0.32%	0.32%
AKRO	B	0.43%	0.18%	0.18%
ALEC	F	0.04%	0.04%	0.04%
ALKS	C	1.13%	0.46%	0.46%
ALLO	F	0.11%	0.04%	0.04%
ALNY	D	2.38%	3.32%	2.38%
AMGN	F	2.28%	7.32%	2.28%
ANAB	F	0.12%	0.05%	0.05%
APLS	F	0.86%	0.29%	0.29%
ARCT	F	0.17%	0.05%	0.05%
ARQT	B	0.42%	0.1%	0.1%
ARWR	D	0.54%	0.25%	0.25%
AVXL	B	0.17%	0.07%	0.07%
BBIO	F	0.87%	0.34%	0.34%
BCRX	D	0.42%	0.15%	0.15%
BEAM	D	0.72%	0.19%	0.19%
BIIB	F	2.19%	2.36%	2.19%
BMRN	F	1.98%	1.21%	1.21%
BPMC	B	1.69%	0.58%	0.58%
CDNA	D	0.24%	0.11%	0.11%
CGEM	F	0.25%	0.06%	0.06%
COGT	D	0.16%	0.08%	0.08%
CRNX	C	0.84%	0.48%	0.48%
CRSP	D	1.63%	0.4%	0.4%
CYTK	F	1.79%	0.62%	0.62%
DAWN	D	0.28%	0.09%	0.09%
DNLI	D	0.46%	0.35%	0.35%
DVAX	C	0.49%	0.17%	0.17%
DYN	F	0.78%	0.21%	0.21%
ERAS	C	0.1%	0.05%	0.05%
ETNB	C	0.16%	0.09%	0.09%
EXEL	B	1.23%	0.97%	0.97%
FDMT	F	0.12%	0.03%	0.03%
FOLD	F	0.63%	0.29%	0.29%
GERN	D	0.86%	0.21%	0.21%
GILD	C	2.9%	9.77%	2.9%
HALO	F	1.27%	0.73%	0.73%
HUMA	F	0.18%	0.05%	0.05%
IDYA	F	0.53%	0.23%	0.23%
IMVT	F	0.62%	0.18%	0.18%
INCY	C	3.29%	1.49%	1.49%
INSM	C	2.43%	1.14%	1.14%
IONS	F	1.08%	0.49%	0.49%
IOVA	F	0.88%	0.23%	0.23%
IRON	B	0.34%	0.1%	0.1%
IRWD	F	0.26%	0.07%	0.07%
ITOS	F	0.06%	0.03%	0.03%
JANX	C	0.51%	0.19%	0.19%
KALV	F	0.07%	0.03%	0.03%
KROS	D	0.36%	0.19%	0.19%
KRYS	C	1.29%	0.44%	0.44%
KURA	F	0.24%	0.12%	0.12%
KYMR	D	0.45%	0.28%	0.28%
MDGL	B	2.17%	0.59%	0.59%
MIRM	B	0.57%	0.16%	0.16%
MNKD	C	0.34%	0.18%	0.18%
MRNA	F	1.57%	1.45%	1.45%
MYGN	F	0.27%	0.14%	0.14%
NBIX	C	2.62%	1.22%	1.22%
NRIX	C	0.33%	0.17%	0.17%
NTLA	F	0.58%	0.16%	0.16%
NTRA	A	3.3%	1.52%	1.52%
NUVL	C	0.6%	0.3%	0.3%
NVAX	F	0.47%	0.13%	0.13%
OLMA	F	0.13%	0.06%	0.06%
ORIC	F	0.09%	0.05%	0.05%
PCVX	D	0.9%	1.03%	0.9%
PRTA	F	0.13%	0.08%	0.08%
PTCT	B	0.64%	0.32%	0.32%
PTGX	D	0.58%	0.23%	0.23%
RARE	F	0.69%	0.4%	0.4%
RCKT	F	0.28%	0.13%	0.13%
RCUS	F	0.2%	0.08%	0.08%
REGN	F	1.8%	5.67%	1.8%
REPL	D	0.18%	0.06%	0.06%
RGNX	D	0.12%	0.05%	0.05%
RLAY	F	0.14%	0.06%	0.06%
RNA	C	1.32%	0.49%	0.49%
ROIV	C	1.18%	0.5%	0.5%
RVMD	C	1.46%	0.8%	0.8%
RXRX	F	0.66%	0.16%	0.16%
RYTM	C	0.61%	0.34%	0.34%
SAGE	F	0.11%	0.03%	0.03%
SANA	F	0.12%	0.03%	0.03%
SMMT	D	0.33%	0.17%	0.17%
SNDX	F	0.44%	0.13%	0.13%
SPRY	C	0.18%	0.08%	0.08%
SRPT	F	2.28%	0.99%	0.99%
SRRK	C	0.49%	0.19%	0.19%
SVRA	F	0.08%	0.03%	0.03%
SWTX	C	0.77%	0.21%	0.21%
TVTX	C	0.26%	0.14%	0.14%
TWST	F	0.93%	0.25%	0.25%
UTHR	C	2.88%	1.7%	1.7%
VCEL	B	0.46%	0.26%	0.26%
VCYT	B	0.53%	0.28%	0.28%
VERA	C	0.57%	0.2%	0.2%
VERV	F	0.15%	0.04%	0.04%
VIR	D	0.2%	0.08%	0.08%
VRTX	D	2.62%	8.08%	2.62%
XNCR	B	0.24%	0.16%	0.16%
YMAB	F	0.06%	0.05%	0.05%

XBI Overweight 22 Positions Relative to IBB

Symbol	Grade	Weight
ABBV	F	2.33%
EXAS	D	2.05%
VKTX	F	2.0%
TGTX	B	1.62%
ARDX	F	0.47%
CGON	F	0.42%
CPRX	C	0.41%
CLDX	F	0.34%
VRDN	D	0.3%
APLT	C	0.22%
CDMO	A	0.22%
EBS	C	0.2%
ALT	C	0.18%
ANNX	F	0.16%
STOK	F	0.16%
MDXG	B	0.16%
IMNM	F	0.13%
OCGN	F	0.12%
CELC	F	0.11%
CCCC	F	0.1%
FATE	F	0.08%
SCLX	F	0.06%

XBI Underweight 78 Positions Relative to IBB

Symbol	Grade	Weight
IQV	F	-3.75%
MTD	F	-2.58%
ILMN	C	-2.27%
WAT	C	-2.22%
TECH	F	-1.13%
CRL	D	-1.07%
MEDP	D	-0.89%
ITCI	C	-0.85%
RGEN	D	-0.75%
BRKR	D	-0.56%
BHVN	D	-0.4%
AXSM	B	-0.38%
XENE	D	-0.31%
MRUS	F	-0.3%
APGE	F	-0.21%
LGND	C	-0.21%
EWTX	C	-0.2%
WVE	C	-0.19%
FTRE	D	-0.19%
GPCR	F	-0.17%
NVCR	C	-0.17%
TARS	C	-0.15%
TXG	F	-0.15%
ARVN	F	-0.15%
ZYME	C	-0.14%
AUPH	B	-0.11%
KNSA	F	-0.09%
ELVN	D	-0.08%
ADPT	C	-0.08%
CTKB	C	-0.08%
CSTL	D	-0.08%
PLRX	D	-0.07%
PACB	F	-0.06%
MRVI	F	-0.06%
NUVB	C	-0.06%
URGN	F	-0.05%
OPK	C	-0.05%
QTRX	F	-0.05%
TSHA	C	-0.04%
FLGT	F	-0.04%
SLRN	F	-0.04%
RVNC	F	-0.04%
TRML	D	-0.04%
TBPH	B	-0.04%
TERN	F	-0.04%
AMLX	C	-0.03%
VNDA	C	-0.03%
DNA	F	-0.03%
MLYS	F	-0.03%
QURE	C	-0.03%
PHAT	F	-0.03%
VYGR	F	-0.03%
MXCT	D	-0.03%
MGTX	C	-0.03%
OKUR	F	-0.02%
ATAI	C	-0.02%
ACRS	B	-0.02%
CABA	F	-0.02%
NAUT	F	-0.02%
CRBU	D	-0.02%
TNGX	F	-0.02%
FULC	F	-0.02%
PRME	F	-0.02%
THRD	F	-0.02%
BMEA	F	-0.02%
ZNTL	F	-0.02%
MGNX	F	-0.02%
AVIR	F	-0.02%
EDIT	F	-0.02%
OVID	F	-0.01%
BLUE	F	-0.01%
CHRS	D	-0.01%
PGEN	F	-0.01%
VTYX	F	-0.01%
LYEL	F	-0.01%
MRNS	F	-0.0%
ALXO	F	-0.0%
RAPT	F	-0.0%