SBIO vs. IBBQ ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to Invesco Nasdaq Biotechnology ETF (IBBQ)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$32.79

Average Daily Volume

11,905

Number of Holdings *

84

* may have additional holdings in another (foreign) market
IBBQ

Invesco Nasdaq Biotechnology ETF

IBBQ Description The investment seeks to track the investment results (before fees and expenses) of the Nasdaq Biotechnology Index ®. The fund generally will invest at least 90% of its total assets in the securities that comprise the index. Strictly in accordance with its guidelines and mandated procedures, Nasdaq compiles the underlying index, which is a modified market capitalization weighted index that is designed to measure the performance of securities listed on the Nasdaq Stock Market that are classified as either biotechnology or pharmaceutical companies. The index may include securities of large-, mid- and small-capitalization companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$20.85

Average Daily Volume

17,636

Number of Holdings *

204

* may have additional holdings in another (foreign) market
Performance
Period SBIO IBBQ
30 Days -8.28% -6.00%
60 Days -13.87% -7.87%
90 Days -1.20% -4.88%
12 Months 7.37% -0.95%
69 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in IBBQ Overlap
ACAD F 1.87% 0.31% 0.31%
ACLX D 1.95% 0.31% 0.31%
AGIO A 1.21% 0.19% 0.19%
AKRO F 0.8% 0.13% 0.13%
ALEC F 0.35% 0.05% 0.05%
ALKS D 2.75% 0.45% 0.45%
ALLO F 0.38% 0.06% 0.06%
ALPN A 2.87% 0.47% 0.47%
ANAB B 0.35% 0.06% 0.06%
ARCT F 0.51% 0.08% 0.08%
ARVN D 1.57% 0.27% 0.27%
AUPH F 0.5% 0.08% 0.08%
AVXL F 0.2% 0.03% 0.03%
AXSM D 2.35% 0.38% 0.38%
BCRX F 0.61% 0.1% 0.1%
BMEA F 0.27% 0.04% 0.04%
CRNX A 2.34% 0.34% 0.34%
DAWN A 0.99% 0.15% 0.15%
DCPH A 0.8% 0.13% 0.13%
DNLI F 1.52% 0.25% 0.25%
ETNB F 0.57% 0.1% 0.1%
EWTX B 0.99% 0.16% 0.16%
FDMT D 0.84% 0.15% 0.15%
FULC D 0.31% 0.05% 0.05%
GERN A 1.3% 0.23% 0.23%
GLPG F 1.32% 0.06% 0.06%
IDYA C 1.95% 0.31% 0.31%
IMCR D 1.94% 0.22% 0.22%
INBX D 1.1% 0.18% 0.18%
IRON F 0.44% 0.07% 0.07%
IRWD F 0.88% 0.14% 0.14%
ITOS D 0.27% 0.04% 0.04%
KNSA C 0.48% 0.08% 0.08%
KROS D 1.35% 0.22% 0.22%
KURA C 0.97% 0.15% 0.15%
MGNX D 0.68% 0.11% 0.11%
MIRM D 0.77% 0.13% 0.13%
MLYS C 0.32% 0.05% 0.05%
MNKD D 0.76% 0.12% 0.12%
MORF F 0.98% 0.16% 0.16%
MRUS C 1.6% 0.26% 0.26%
NTLA D 1.4% 0.23% 0.23%
OLMA D 0.37% 0.06% 0.06%
PCVX D 4.47% 0.75% 0.75%
PLRX F 0.51% 0.08% 0.08%
PRTA F 0.75% 0.13% 0.13%
PTGX D 1.06% 0.17% 0.17%
RAPT F 0.19% 0.03% 0.03%
REPL F 0.27% 0.04% 0.04%
RNA A 1.36% 0.21% 0.21%
RPHM D 0.04% 0.01% 0.01%
RVMD A 4.05% 0.67% 0.67%
RYTM C 1.63% 0.26% 0.26%
SMMT C 1.77% 0.27% 0.27%
SNDX C 1.21% 0.2% 0.2%
SPRY C 0.55% 0.09% 0.09%
SVRA D 0.43% 0.07% 0.07%
SWTX C 2.2% 0.35% 0.35%
TARS D 0.86% 0.12% 0.12%
TVTX F 0.3% 0.05% 0.05%
VCEL C 1.52% 0.24% 0.24%
VERA D 1.47% 0.23% 0.23%
VIR F 0.74% 0.12% 0.12%
VNDA B 0.18% 0.03% 0.03%
VRNA F 0.85% 0.12% 0.12%
XENE C 2.1% 0.34% 0.34%
XNCR C 0.76% 0.12% 0.12%
ZLAB F 1.01% 0.08% 0.08%
ZNTL F 0.6% 0.1% 0.1%
SBIO Overweight 15 Positions Relative to IBBQ
Symbol Grade Weight
CERE A 5.17%
VKTX B 4.62%
CLDX D 1.65%
CORT D 1.61%
CPRX D 1.18%
RCUS D 0.95%
LQDA D 0.67%
MDXG F 0.65%
VRDN F 0.61%
OPK C 0.59%
AVTE D 0.44%
CMPS C 0.36%
AURA D 0.24%
ENTA D 0.19%
INZY F 0.18%
SBIO Underweight 135 Positions Relative to IBBQ
Symbol Grade Weight
AMGN C -8.69%
VRTX D -8.31%
REGN C -8.16%
GILD F -8.12%
AZN A -4.56%
MRNA A -4.46%
BIIB C -3.15%
ILMN D -2.13%
ALNY F -2.05%
BMRN D -1.88%
NBIX B -1.49%
VTRS C -1.49%
SNY C -1.44%
RPRX D -1.39%
INCY F -1.3%
MEDP C -1.29%
ARGX D -1.28%
SRPT B -1.23%
UTHR B -1.23%
BNTX F -0.95%
ASND D -0.91%
ITCI B -0.81%
EXEL A -0.77%
JAZZ F -0.76%
CYTK D -0.76%
IONS F -0.67%
APLS F -0.64%
BPMC B -0.62%
BGNE D -0.61%
HALO D -0.55%
CRSP F -0.5%
BBIO D -0.49%
KRYS D -0.49%
MDGL D -0.48%
IMVT F -0.47%
LEGN F -0.42%
NUVL C -0.42%
INSM D -0.4%
RARE D -0.4%
FOLD F -0.36%
FTRE C -0.35%
IOVA C -0.35%
ARWR F -0.33%
JANX A -0.28%
GH D -0.24%
RCKT F -0.24%
DYN C -0.23%
KYMR D -0.23%
AMPH D -0.22%
BEAM F -0.22%
PTCT B -0.22%
SANA C -0.2%
MYGN C -0.19%
HRMY D -0.19%
TWST C -0.19%
RXRX D -0.19%
SUPN C -0.18%
VCYT F -0.17%
ARDX D -0.17%
DVAX F -0.17%
FUSN A -0.17%
ADMA A -0.16%
ANIP B -0.15%
LGND D -0.14%
PCRX F -0.14%
GMAB F -0.14%
NVCR F -0.14%
ABCL F -0.13%
COLL C -0.12%
MRVI B -0.11%
SRRK C -0.11%
ARQT D -0.1%
INVA A -0.1%
SAGE F -0.09%
RLAY D -0.09%
BCYC C -0.09%
EYPT C -0.09%
ALXO A -0.08%
RGNX F -0.08%
ELVN A -0.08%
COGT F -0.08%
GRFS D -0.08%
SIGA A -0.07%
ORIC D -0.07%
WVE D -0.07%
LYEL D -0.07%
AUTL F -0.07%
YMAB C -0.07%
EOLS C -0.07%
NRIX D -0.07%
CGEM A -0.07%
PHAT F -0.06%
HCM A -0.06%
OABI F -0.06%
CSTL B -0.06%
CVAC F -0.06%
PRME F -0.06%
OCUL F -0.06%
CNTA D -0.06%
CABA F -0.06%
NVAX F -0.06%
VERV F -0.06%
LXRX F -0.05%
PACB F -0.05%
ABUS D -0.05%
URGN F -0.05%
TSHA C -0.05%
EDIT F -0.05%
TBPH F -0.05%
THRD B -0.05%
KALV C -0.05%
PETQ F -0.05%
RVNC F -0.04%
AMRN D -0.04%
PGEN F -0.04%
CRBU F -0.04%
ADPT F -0.04%
HROW F -0.04%
HUMA A -0.04%
VYGR D -0.04%
QURE F -0.03%
CHRS F -0.03%
ACIU D -0.03%
XERS F -0.03%
VTYX F -0.03%
PAHC A -0.03%
ERAS D -0.03%
TERN F -0.03%
ATAI C -0.03%
MGTX F -0.03%
ME F -0.02%
BLUE F -0.02%
OVID F -0.02%
MRNS F -0.01%
ACRS F -0.01%
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