SBIO vs. BIB ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to ProShares Ultra Nasdaq Biotechnology (BIB)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$31.50

Average Daily Volume

12,975

Number of Holdings *

84

* may have additional holdings in another (foreign) market
BIB

ProShares Ultra Nasdaq Biotechnology

BIB Description The investment seeks daily investment results that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology Index®. The fund invests in securities and derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times (2x) the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$47.82

Average Daily Volume

37,381

Number of Holdings *

204

* may have additional holdings in another (foreign) market
Performance
Period SBIO BIB
30 Days -9.22% -14.44%
60 Days -12.18% -16.57%
90 Days 0.02% -16.52%
12 Months 5.77% -16.49%
69 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in BIB Overlap
ACAD F 1.89% 0.23% 0.23%
ACLX D 1.96% 0.25% 0.25%
AGIO B 1.09% 0.13% 0.13%
AKRO F 0.82% 0.1% 0.1%
ALEC F 0.34% 0.04% 0.04%
ALKS F 2.67% 0.33% 0.33%
ALLO F 0.4% 0.05% 0.05%
ALPN A 2.84% 0.34% 0.34%
ANAB D 0.38% 0.05% 0.05%
ARCT F 0.54% 0.06% 0.06%
ARVN D 1.53% 0.19% 0.19%
AUPH F 0.49% 0.06% 0.06%
AVXL F 0.23% 0.03% 0.03%
AXSM F 2.19% 0.26% 0.26%
BCRX F 0.64% 0.08% 0.08%
BMEA F 0.29% 0.04% 0.04%
CRNX A 2.28% 0.25% 0.25%
DAWN B 0.86% 0.1% 0.1%
DCPH D 0.81% 0.1% 0.1%
DNLI F 1.62% 0.2% 0.2%
ETNB F 0.59% 0.07% 0.07%
EWTX D 1.04% 0.13% 0.13%
FDMT D 0.9% 0.11% 0.11%
FULC D 0.31% 0.04% 0.04%
GERN A 1.31% 0.15% 0.15%
GLPG F 1.31% 0.05% 0.05%
IDYA D 2.04% 0.25% 0.25%
IMCR D 1.79% 0.16% 0.16%
INBX C 1.1% 0.13% 0.13%
IRON F 0.49% 0.06% 0.06%
IRWD F 0.83% 0.1% 0.1%
ITOS D 0.27% 0.03% 0.03%
KNSA D 0.47% 0.06% 0.06%
KROS D 1.4% 0.17% 0.17%
KURA D 0.95% 0.12% 0.12%
MGNX B 0.7% 0.09% 0.09%
MIRM F 0.75% 0.09% 0.09%
MLYS F 0.33% 0.04% 0.04%
MNKD D 0.74% 0.09% 0.09%
MORF F 0.94% 0.12% 0.12%
MRUS D 1.57% 0.2% 0.2%
NTLA F 1.41% 0.18% 0.18%
OLMA F 0.4% 0.05% 0.05%
PCVX D 4.53% 0.55% 0.55%
PLRX F 0.54% 0.07% 0.07%
PRTA F 0.77% 0.1% 0.1%
PTGX D 1.02% 0.13% 0.13%
RAPT F 0.19% 0.02% 0.02%
REPL F 0.3% 0.04% 0.04%
RNA A 1.28% 0.16% 0.16%
RPHM C 0.04% 0.0% 0.0%
RVMD A 4.01% 0.48% 0.48%
RYTM D 1.56% 0.2% 0.2%
SMMT D 1.67% 0.21% 0.21%
SNDX D 1.22% 0.15% 0.15%
SPRY B 0.59% 0.07% 0.07%
SVRA C 0.47% 0.06% 0.06%
SWTX D 2.15% 0.26% 0.26%
TARS B 0.88% 0.1% 0.1%
TVTX F 0.31% 0.04% 0.04%
VCEL B 1.54% 0.19% 0.19%
VERA D 1.57% 0.2% 0.2%
VIR F 0.76% 0.09% 0.09%
VNDA A 0.16% 0.02% 0.02%
VRNA F 0.88% 0.09% 0.09%
XENE D 2.1% 0.25% 0.25%
XNCR F 0.78% 0.1% 0.1%
ZLAB F 0.96% 0.06% 0.06%
ZNTL F 0.61% 0.08% 0.08%
SBIO Overweight 15 Positions Relative to BIB
Symbol Grade Weight
CERE B 5.04%
VKTX B 4.79%
CLDX D 1.67%
CORT F 1.63%
CPRX A 1.23%
RCUS F 0.97%
LQDA D 0.69%
VRDN F 0.64%
MDXG F 0.62%
OPK C 0.57%
AVTE B 0.44%
CMPS F 0.38%
AURA F 0.24%
ENTA C 0.22%
INZY F 0.2%
SBIO Underweight 135 Positions Relative to BIB
Symbol Grade Weight
AMGN D -6.2%
VRTX C -6.04%
GILD F -6.01%
REGN C -5.95%
AZN A -3.27%
MRNA A -3.24%
BIIB F -2.34%
ILMN F -1.57%
ALNY F -1.52%
BMRN A -1.41%
VTRS D -1.1%
NBIX C -1.07%
RPRX D -1.03%
SNY D -1.03%
INCY F -0.98%
MEDP B -0.97%
ARGX F -0.96%
SRPT D -0.91%
UTHR A -0.9%
BNTX F -0.69%
ASND C -0.68%
CYTK D -0.57%
EXEL A -0.56%
JAZZ F -0.56%
APLS F -0.51%
ITCI A -0.51%
IONS D -0.49%
BGNE F -0.47%
BPMC A -0.43%
HALO D -0.4%
KRYS A -0.39%
MDGL D -0.38%
CRSP F -0.38%
BBIO F -0.37%
IMVT F -0.36%
LEGN F -0.34%
INSM D -0.33%
NUVL D -0.31%
RARE D -0.29%
FTRE B -0.28%
IOVA D -0.27%
FOLD D -0.26%
ARWR F -0.24%
JANX A -0.21%
RCKT D -0.18%
DYN B -0.17%
GH F -0.17%
BEAM F -0.17%
KYMR D -0.17%
AMPH F -0.16%
PTCT F -0.16%
SANA D -0.15%
HRMY D -0.14%
TWST D -0.14%
MYGN D -0.14%
RXRX F -0.14%
FUSN A -0.13%
ARDX D -0.13%
SUPN D -0.13%
LGND B -0.12%
VCYT F -0.12%
DVAX D -0.12%
NVCR F -0.11%
ADMA A -0.11%
ANIP A -0.11%
ABCL F -0.1%
PCRX F -0.1%
GMAB D -0.1%
MRVI C -0.09%
COLL B -0.09%
SAGE F -0.08%
SRRK D -0.08%
ARQT B -0.08%
EYPT D -0.08%
GRFS F -0.07%
RGNX F -0.07%
ELVN B -0.07%
OCUL D -0.07%
RLAY F -0.07%
INVA C -0.07%
COGT D -0.06%
EOLS D -0.06%
AUTL D -0.06%
CABA F -0.06%
WVE D -0.06%
CGEM B -0.06%
NRIX A -0.06%
PACB F -0.06%
BCYC B -0.06%
PHAT D -0.05%
OABI F -0.05%
NVAX F -0.05%
CVAC F -0.05%
CNTA B -0.05%
LYEL B -0.05%
VERV F -0.05%
SIGA A -0.05%
PRME F -0.05%
ALXO B -0.05%
ORIC D -0.05%
YMAB C -0.05%
HROW D -0.04%
VYGR F -0.04%
LXRX F -0.04%
URGN D -0.04%
PETQ F -0.04%
THRD A -0.04%
KALV D -0.04%
TBPH B -0.04%
TSHA B -0.04%
EDIT F -0.04%
ABUS B -0.04%
CSTL D -0.04%
HCM A -0.04%
TERN F -0.03%
ATAI B -0.03%
MGTX F -0.03%
PGEN F -0.03%
RVNC F -0.03%
AMRN F -0.03%
CRBU F -0.03%
ADPT F -0.03%
BLUE F -0.02%
OVID D -0.02%
QURE F -0.02%
CHRS F -0.02%
ACIU F -0.02%
XERS F -0.02%
PAHC A -0.02%
VTYX F -0.02%
HUMA B -0.02%
ERAS F -0.02%
MRNS F -0.01%
ACRS D -0.01%
ME F -0.01%
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