OZEM vs. THNR ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to Amplify Weight Loss Drug & Treatment ETF (THNR)

OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$26.27

Average Daily Volume

82,294

Number of Holdings ^*

7

* may have additional holdings in another (foreign) market

THNR

Amplify Weight Loss Drug & Treatment ETF

THNR Description

The fund's manager invests at least 80% of its net assets (plus borrowings for investment purposes) in securities that comprise the index. The index is comprised of global companies who are manufacturers in the GLP-1 agonist pharmaceutical business or who enable such business. GLP-1 agonists (glucagon-like peptide) seek to lower blood sugar levels and reduce appetite and promote fullness, with the ultimate potential for weight loss. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$25.97

Average Daily Volume

7,926

Number of Holdings ^*

7

* may have additional holdings in another (foreign) market

Performance

Period	OZEM	THNR
30 Days	4.45%	2.70%
60 Days
90 Days
12 Months

3 Overlapping Holdings

	Symbol	Grade	Weight in OZEM	Weight in THNR	Overlap
	AMGN	B	4.2%	5.57%	4.2%
	LLY	B	21.39%	15.58%	15.58%
	NVO	A	20.52%	14.9%	14.9%

OZEM Overweight 4 Positions Relative to THNR

	Symbol	Grade	Weight
	ALT	F	3.97%
	TERN	C	3.32%
	VKTX	D	3.27%
	GPCR	C	3.14%

OZEM Underweight 4 Positions Relative to THNR

	Symbol	Grade	Weight
	PFE	C	-5.32%
	MRK	A	-5.02%
	CTLT	B	-4.75%
	TMO	D	-4.72%

OZEM: Top Represented Industries & Keywords

Industries: Biotechnology Drug Manufacturers - Major

Keywords: Obesity Biopharmaceutical Diabetes Medicine Pharmaceutical Products Anti Diabetic Drugs Glucagon Growth Hormone Hepatitis Inflammation Life Sciences Neuroscience Non Alcoholic Fatty Liver Disease Peptide Hormones Pulmonary Arterial Hypertension S&P 500 Steatohepatitis Wholesale Distributor Alcohol Alzheimer's Disease

THNR: Top Represented Industries & Keywords

Industries: Drug Manufacturers - Major Biotechnology Diagnostics & Research Drug Manufacturers - Specialty & Generic

Keywords: S&P 500 Pharmaceutical Products Obesity Animal Health Biopharmaceutical Biotechnology Diabetes Health Products Inflammation Life Sciences Neuroscience Alzheimer's Disease Animal Health Products Antibiotics Clinic Depressive Disorder Dow Jones Component Dysfunction Erectile Dysfunction Growth Hormone