LABU vs. BBC ETF Comparison

Comparison of Direxion Daily S&P Biotech Bull 3X Shares (LABU) to Virtus LifeSci Biotech Clinical Trials ETF (BBC)

LABU

Direxion Daily S&P Biotech Bull 3X Shares

LABU Description

The investment seeks daily investment results, of 300% of the performance of the S&P Biotechnology Select Industry Index ("index"). The index is provided by S&P and includes domestic companies from the biotechnology industry. The fund normally creates long positions by investing at least 80% of its assets in the securities that comprise the index and/or financial instruments that provide leveraged and unleveraged exposure to the index. These financial instruments include: swap agreements; options on securities and indices; forward contracts; reverse repurchase agreements; ETFs; and other financial instruments. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$90.87

Average Daily Volume

2,663,991

Number of Holdings ^*

125

* may have additional holdings in another (foreign) market

BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description

The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$26.09

Average Daily Volume

4,123

Number of Holdings ^*

90

* may have additional holdings in another (foreign) market

Performance

Period	LABU	BBC
30 Days	-31.53%	-10.43%
60 Days	-45.21%	-16.77%
90 Days	-18.46%	2.80%
12 Months	-23.76%	10.76%

67 Overlapping Holdings

	Symbol	Grade	Weight in LABU	Weight in BBC	Overlap
	ACLX	D	0.58%	0.9%	0.58%
	AKRO	F	0.54%	0.8%	0.54%
	ALEC	F	0.13%	0.56%	0.13%
	ALLO	F	0.23%	1.05%	0.23%
	ALPN	A	1.33%	2.89%	1.33%
	ANAB	B	0.16%	0.85%	0.16%
	ARCT	F	0.37%	0.84%	0.37%
	ARDX	D	0.6%	0.93%	0.6%
	ARWR	F	0.58%	0.7%	0.58%
	BEAM	F	0.52%	0.67%	0.52%
	BMEA	F	0.46%	0.66%	0.46%
	CABA	F	0.41%	0.55%	0.41%
	CGEM	A	0.13%	1.66%	0.13%
	CLDX	D	0.65%	0.88%	0.65%
	COGT	F	0.44%	1.19%	0.44%
	CRBU	F	0.19%	0.55%	0.19%
	CRNX	A	0.83%	1.07%	0.83%
	CYTK	D	0.81%	1.52%	0.81%
	DAWN	A	0.26%	0.99%	0.26%
	DNLI	F	0.61%	0.59%	0.59%
	DVAX	F	0.73%	0.73%	0.73%
	DYN	C	0.75%	1.82%	0.75%
	EDIT	F	0.4%	0.43%	0.4%
	ETNB	F	0.38%	0.7%	0.38%
	FDMT	D	0.36%	1.26%	0.36%
	GERN	A	0.79%	1.34%	0.79%
	IDYA	C	0.66%	0.97%	0.66%
	IMVT	F	0.73%	0.57%	0.57%
	INBX	D	0.61%	1.05%	0.61%
	IOVA	C	0.58%	1.3%	0.58%
	IRON	F	0.24%	0.39%	0.24%
	KROS	D	0.59%	1.38%	0.59%
	KRYS	D	0.74%	1.18%	0.74%
	KURA	C	0.5%	1.33%	0.5%
	KYMR	D	0.64%	1.19%	0.64%
	MDGL	D	0.67%	0.78%	0.67%
	MGNX	D	0.48%	1.48%	0.48%
	MORF	F	0.55%	0.82%	0.55%
	NRIX	D	0.25%	1.34%	0.25%
	NTLA	D	0.59%	0.57%	0.57%
	NUVL	C	0.62%	0.72%	0.62%
	NVAX	F	0.6%	0.62%	0.6%
	OLMA	D	0.26%	0.69%	0.26%
	ORIC	D	0.09%	0.81%	0.09%
	PCVX	D	0.68%	0.85%	0.68%
	PRTA	F	0.57%	0.45%	0.45%
	PTGX	D	0.56%	1.09%	0.56%
	RCKT	F	0.69%	0.71%	0.69%
	RCUS	D	0.44%	0.74%	0.44%
	REPL	F	0.36%	0.7%	0.36%
	RGNX	F	0.25%	0.65%	0.25%
	RLAY	D	0.24%	0.5%	0.24%
	RNA	A	0.43%	2.65%	0.43%
	RVMD	A	0.91%	1.17%	0.91%
	RXRX	D	0.55%	0.68%	0.55%
	SANA	C	0.35%	1.72%	0.35%
	SMMT	C	0.2%	1.19%	0.2%
	SNDX	C	0.69%	0.89%	0.69%
	SRRK	C	0.43%	0.67%	0.43%
	TGTX	D	0.68%	0.67%	0.67%
	VERA	D	0.6%	2.27%	0.6%
	VERV	F	0.26%	0.41%	0.26%
	VIR	F	0.31%	0.68%	0.31%
	VKTX	B	0.72%	2.86%	0.72%
	VRDN	F	0.51%	0.62%	0.51%
	XNCR	C	0.37%	0.73%	0.37%
	ZNTL	F	0.34%	0.71%	0.34%

LABU Overweight 58 Positions Relative to BBC

	Symbol	Grade	Weight
	EXAS	F	0.84%
	BMRN	D	0.84%
	EXEL	A	0.83%
	MRNA	A	0.82%
	CERE	A	0.82%
	AMGN	C	0.8%
	NTRA	A	0.8%
	BPMC	B	0.79%
	UTHR	B	0.78%
	VRTX	D	0.78%
	ALNY	F	0.78%
	NBIX	B	0.77%
	ABBV	C	0.76%
	SRPT	B	0.76%
	HALO	D	0.75%
	REGN	C	0.75%
	RYTM	C	0.75%
	IONS	F	0.75%
	GILD	F	0.72%
	IRWD	F	0.72%
	FOLD	F	0.71%
	RARE	D	0.7%
	INCY	F	0.7%
	BBIO	D	0.7%
	INSM	D	0.7%
	BIIB	C	0.7%
	VCEL	C	0.69%
	SWTX	C	0.68%
	PTCT	B	0.67%
	ALKS	D	0.66%
	CPRX	D	0.65%
	ARQT	D	0.65%
	TWST	C	0.63%
	APLS	F	0.62%
	BCRX	F	0.61%
	AGIO	A	0.59%
	ALT	D	0.58%
	ACAD	F	0.58%
	MIRM	D	0.57%
	CRSP	F	0.57%
	VCYT	F	0.54%
	CCCC	D	0.5%
	SAGE	F	0.44%
	MYGN	C	0.4%
	ADMA	A	0.37%
	TVTX	F	0.31%
	FATE	F	0.31%
	CDMO	D	0.3%
	DCPH	A	0.28%
	CDNA	F	0.26%
	MNKD	D	0.26%
	AVXL	F	0.22%
	KNSA	C	0.21%
	MDXG	F	0.16%
	MRSN	D	0.1%
	VYGR	D	0.08%
	SPRY	C	0.08%
	RCEL	F	0.04%

LABU Underweight 23 Positions Relative to BBC

	Symbol	Grade	Weight
	LQDA	D	-1.5%
	MRUS	C	-1.37%
	BCYC	C	-1.28%
	MLYS	C	-1.17%
	LYEL	D	-1.02%
	IGMS	D	-1.0%
	ALXO	A	-0.99%
	PGEN	F	-0.94%
	IMTX	F	-0.9%
	CMPS	C	-0.9%
	PHAT	F	-0.86%
	ITOS	D	-0.86%
	XENE	C	-0.84%
	ARVN	D	-0.81%
	BLTE	C	-0.71%
	PLRX	F	-0.63%
	TERN	F	-0.61%
	ABCL	F	-0.61%
	SAVA	B	-0.58%
	QURE	F	-0.5%
	CVAC	F	-0.38%
	RAPT	F	-0.35%
	ALLK	F	-0.28%

LABU: Top Represented Industries & Keywords

Industries: Biotechnology Diagnostics & Research Drug Manufacturers - Major Drug Manufacturers - Specialty & Generic Medical Devices

Keywords: Biopharmaceutical Biotechnology Medicine Cancer Life Sciences Clinical Medicine Biology Immune System Clinical Development Immunology Solid Tumors Disease Antibodies Organ Systems Monoclonal Antibodies Treatment Of Cancer Autoimmune Disease Monoclonal Antibody Enzymes Genetics

BBC: Top Represented Industries & Keywords

Industries: Biotechnology Diagnostics & Research Drug Manufacturers - Specialty & Generic Medical Care Facilities

Keywords: Biopharmaceutical Biotechnology Medicine Cancer Clinical Medicine Life Sciences Solid Tumors Disease Immune System Biology Immunology Antibodies Treatment Of Cancer Clinical Development Cancer Treatment Genetics Medication Monoclonal Antibodies Autoimmune Disease Cancer Immunotherapy