BTEC vs. SBIO ETF Comparison

Comparison of Principal Healthcare Innovators Index ETF (BTEC) to ALPS Medical Breakthroughs ETF (SBIO)
BTEC

Principal Healthcare Innovators Index ETF

BTEC Description

The investment seeks to provide investment results that closely correspond, before expenses, to the performance of the Nasdaq Healthcare Innovators Index (the "index"). Under normal circumstances, the fund invests at least 80% of its net assets, plus any borrowings for investment purposes, in equity securities of companies that compose the index at the time of purchase. The index uses a quantitative model designed to identify equity securities in the Nasdaq US Benchmark Index (including growth and value stock) that are small and medium capitalization U.S. healthcare companies.

Grade (RS Rating)

Last Trade

$33.60

Average Daily Volume

6,193

Number of Holdings *

245

* may have additional holdings in another (foreign) market
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$31.53

Average Daily Volume

12,312

Number of Holdings *

84

* may have additional holdings in another (foreign) market
Performance
Period BTEC SBIO
30 Days -9.33% -9.21%
60 Days -11.16% -11.48%
90 Days -6.60% -3.86%
12 Months -2.07% 6.55%
66 Overlapping Holdings
Symbol Grade Weight in BTEC Weight in SBIO Overlap
ACLX D 0.67% 1.95% 0.67%
AGIO A 0.39% 1.21% 0.39%
AKRO F 0.35% 0.8% 0.35%
ALEC F 0.14% 0.35% 0.14%
ALLO F 0.15% 0.38% 0.15%
ALPN A 0.96% 2.87% 0.96%
ANAB F 0.15% 0.35% 0.15%
ARCT F 0.2% 0.51% 0.2%
ARVN D 0.54% 1.57% 0.54%
AUPH F 0.19% 0.5% 0.19%
AURA F 0.11% 0.24% 0.11%
AVTE D 0.18% 0.44% 0.18%
AVXL F 0.1% 0.2% 0.1%
AXSM D 0.72% 2.35% 0.72%
BCRX F 0.24% 0.61% 0.24%
BMEA F 0.12% 0.27% 0.12%
CERE A 1.67% 5.17% 1.67%
CLDX D 0.57% 1.65% 0.57%
CRNX B 0.76% 2.34% 0.76%
DAWN F 0.29% 0.99% 0.29%
DCPH D 0.29% 0.8% 0.29%
DNLI F 0.56% 1.52% 0.56%
ENTA F 0.1% 0.19% 0.1%
ETNB F 0.22% 0.57% 0.22%
EWTX C 0.36% 0.99% 0.36%
FDMT D 0.31% 0.84% 0.31%
GERN B 0.44% 1.3% 0.44%
IDYA D 0.7% 1.95% 0.7%
INBX D 0.39% 1.1% 0.39%
INZY F 0.08% 0.18% 0.08%
IRON F 0.18% 0.44% 0.18%
ITOS F 0.12% 0.27% 0.12%
KNSA D 0.18% 0.48% 0.18%
KROS D 0.47% 1.35% 0.47%
KURA C 0.34% 0.97% 0.34%
LQDA D 0.25% 0.67% 0.25%
MGNX D 0.26% 0.68% 0.26%
MIRM D 0.27% 0.77% 0.27%
MLYS F 0.16% 0.32% 0.16%
MORF F 0.34% 0.98% 0.34%
NTLA F 0.5% 1.4% 0.5%
OLMA F 0.16% 0.37% 0.16%
PCVX D 1.49% 4.47% 1.49%
PLRX F 0.2% 0.51% 0.2%
PRTA F 0.28% 0.75% 0.28%
PTGX D 0.36% 1.06% 0.36%
RAPT F 0.09% 0.19% 0.09%
RCUS F 0.35% 0.95% 0.35%
REPL F 0.12% 0.27% 0.12%
RNA B 0.44% 1.36% 0.44%
RVMD B 1.3% 4.05% 1.3%
RYTM D 0.55% 1.63% 0.55%
SMMT D 0.58% 1.77% 0.58%
SNDX D 0.42% 1.21% 0.42%
SPRY D 0.22% 0.55% 0.22%
SVRA D 0.18% 0.43% 0.18%
SWTX C 0.7% 2.2% 0.7%
TARS D 0.31% 0.86% 0.31%
TVTX F 0.13% 0.3% 0.13%
VCEL D 0.54% 1.52% 0.54%
VERA D 0.58% 1.47% 0.58%
VIR F 0.28% 0.74% 0.28%
VKTX B 1.61% 4.62% 1.61%
VRDN F 0.24% 0.61% 0.24%
XNCR D 0.29% 0.76% 0.29%
ZNTL F 0.23% 0.6% 0.23%
BTEC Overweight 179 Positions Relative to SBIO
Symbol Grade Weight
ALNY F 3.23%
MRNA A 3.18%
ILMN D 2.88%
EXAS F 2.59%
SRPT B 2.43%
NTRA A 2.39%
CTLT C 2.22%
CYTK D 1.54%
ELAN F 1.5%
INSP B 1.46%
ITCI B 1.38%
APLS F 1.37%
IONS D 1.34%
BPMC B 1.15%
GKOS A 1.07%
BBIO F 1.05%
MDGL F 1.02%
IMVT F 0.99%
INSM D 0.89%
NUVL C 0.85%
RARE D 0.79%
TXG F 0.77%
IRTC B 0.76%
IOVA D 0.74%
FOLD F 0.71%
ENOV D 0.7%
TMDX A 0.69%
ARWR F 0.67%
AZTA F 0.67%
JANX B 0.62%
PRCT A 0.59%
ICUI F 0.53%
NARI F 0.52%
RCKT F 0.5%
TGTX D 0.5%
BEAM F 0.48%
TNDM A 0.48%
KYMR D 0.48%
DYN D 0.47%
RXST B 0.46%
PTCT F 0.45%
SANA C 0.43%
ATEC F 0.42%
MYGN F 0.4%
TWST C 0.39%
ARDX D 0.37%
RXRX D 0.37%
VCYT F 0.34%
NVCR F 0.32%
ADMA A 0.32%
OCUL F 0.28%
ARQT D 0.28%
ATRC F 0.26%
MRVI D 0.26%
EYPT D 0.26%
SRRK C 0.25%
RGNX F 0.22%
SAVA B 0.22%
AVNS F 0.22%
RLAY F 0.22%
SAGE F 0.22%
CYRX D 0.21%
ELVN B 0.21%
CABA F 0.2%
CTKB F 0.2%
FNA F 0.2%
TMCI F 0.19%
KIDS C 0.19%
PACB F 0.19%
TYRA D 0.19%
NRIX B 0.19%
BLFS C 0.18%
WVE F 0.18%
SILK B 0.18%
CGEM A 0.18%
EOLS D 0.18%
SIGA A 0.17%
YMAB D 0.17%
ALXO A 0.17%
HLVX F 0.17%
COGT F 0.17%
NKTX D 0.16%
LBPH C 0.16%
NUVB B 0.16%
ORIC F 0.16%
QTRX F 0.16%
PRME F 0.16%
SIBN F 0.16%
LYEL C 0.16%
ABUS B 0.15%
NVAX F 0.15%
OABI F 0.15%
PHAT F 0.15%
TBPH B 0.14%
KALV F 0.14%
VERV F 0.14%
THRD B 0.14%
URGN F 0.14%
FATE F 0.14%
HRTX B 0.13%
LRMR D 0.13%
EDIT F 0.13%
OFIX F 0.13%
ADPT F 0.12%
CELC D 0.12%
PLSE F 0.12%
ZIMV D 0.12%
TRDA F 0.12%
ANNX D 0.12%
HROW F 0.12%
LXRX F 0.12%
VYGR F 0.12%
CDMO D 0.12%
NVRO F 0.12%
MRSN D 0.12%
SRDX F 0.11%
ALT D 0.11%
ANIK B 0.11%
PEPG D 0.11%
RVNC F 0.11%
CDNA F 0.11%
CERS D 0.1%
IGMS F 0.1%
TNYA D 0.1%
HUMA B 0.1%
CRMD B 0.1%
MGTX F 0.1%
CVRX F 0.1%
CRBU F 0.1%
PGEN C 0.1%
VTYX F 0.09%
LUNG F 0.09%
ANGO D 0.09%
FENC D 0.09%
ALDX C 0.09%
AXGN F 0.09%
TERN F 0.09%
ERAS F 0.09%
OMER F 0.08%
MACK B 0.08%
ARAY F 0.08%
STRO F 0.08%
CHRS F 0.08%
XERS F 0.08%
ATNM D 0.08%
TSVT F 0.08%
KOD F 0.07%
SCPH F 0.07%
RIGL F 0.07%
BLUE F 0.07%
ACET F 0.07%
AKYA F 0.07%
QSI F 0.07%
RCEL F 0.07%
XFOR B 0.07%
PSTX F 0.07%
BFLY F 0.06%
INGN D 0.06%
CDXS D 0.06%
EBS F 0.05%
ALLK F 0.05%
PMVP D 0.05%
ACRS F 0.05%
ATRA F 0.05%
SGMO F 0.05%
BTAI F 0.05%
OM F 0.05%
KPTI F 0.05%
OMGA F 0.05%
CUTR F 0.05%
BCAB F 0.05%
GNLX F 0.04%
MURA F 0.04%
PDSB F 0.04%
MCRB F 0.04%
FGEN F 0.04%
MRNS F 0.02%
EYEN F 0.02%
GRTS F 0.02%
BTEC Underweight 18 Positions Relative to SBIO
Symbol Grade Weight
ALKS D -2.75%
XENE D -2.1%
IMCR D -1.94%
ACAD F -1.87%
CORT F -1.61%
MRUS C -1.6%
GLPG F -1.32%
CPRX D -1.18%
ZLAB F -1.01%
IRWD D -0.88%
VRNA F -0.85%
MNKD C -0.76%
MDXG F -0.65%
OPK C -0.59%
CMPS F -0.36%
FULC D -0.31%
VNDA B -0.18%
RPHM D -0.04%
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