BIS vs. PBE ETF Comparison

Comparison of ProShares UltraShort Nasdaq Biotechnology (BIS) to PowerShares Dynamic Biotech & Genome (PBE)
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description

The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$15.54

Average Daily Volume

13,954

Number of Holdings *

73

* may have additional holdings in another (foreign) market
PBE

PowerShares Dynamic Biotech & Genome

PBE Description The PowerShares Dynamic Biotechnology & Genome Portfolio (Fund) is based on the Dynamic Biotech & Genome IntellidexSM Index (Intellidex Index). The Fund will normally invest at least 90% of its total assets in common stocks that comprise the Index. The Intellidex Index is designed to provide capital appreciation by thoroughly evaluating companies based on a variety of investment merit criteria, including price momentum, earnings momentum, quality, management action, and value. The Underlying Intellidex Index is comprised of common stocks of 30 US biotechnology and genome companies. These are companies that are principally engaged in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes and companies that benefit significantly from scientific and technological advances biotechnology and genetic engineering and reseach. The Fund and the Index are rebalanced and reconstituted quarterly in February, May, August and November.

Grade (RS Rating)

Last Trade

$69.14

Average Daily Volume

6,628

Number of Holdings *

30

* may have additional holdings in another (foreign) market
Performance
Period BIS PBE
30 Days 1.97% -0.97%
60 Days 8.40% -3.80%
90 Days 1.66% 0.98%
12 Months -33.52% 26.96%
17 Overlapping Holdings
Symbol Grade Weight in BIS Weight in PBE Overlap
ACAD F 0.81% 2.62% 0.81%
ALNY C 1.6% 5.57% 1.6%
AMGN C 8.14% 5.1% 5.1%
BIIB F 6.12% 4.77% 4.77%
BMRN F 1.91% 4.1% 1.91%
BPMC C 0.48% 2.62% 0.48%
EXEL A 0.73% 3.18% 0.73%
HALO B 0.35% 2.32% 0.35%
ILMN A 5.67% 5.78% 5.67%
INCY A 2.09% 2.87% 2.09%
MYGN F 0.26% 2.34% 0.26%
NBIX C 1.16% 4.0% 1.16%
REGN F 4.13% 4.15% 4.13%
TECH B 1.02% 2.82% 1.02%
UTHR A 0.49% 5.35% 0.49%
VCYT A 0.18% 2.93% 0.18%
XNCR A 0.26% 3.55% 0.26%
BIS Overweight 56 Positions Relative to PBE
Symbol Grade Weight
GILD A 7.41%
VRTX D 7.21%
VTRS B 1.35%
SNY D 1.29%
SRPT D 1.15%
NVCR F 1.1%
JAZZ D 1.03%
IONS F 1.02%
GH D 0.96%
AMRN F 0.85%
MRNA F 0.83%
BGNE C 0.83%
ASND F 0.77%
ARWR F 0.65%
BLUE F 0.65%
BBIO D 0.51%
ALLK B 0.49%
NKTR C 0.48%
SAGE F 0.48%
FGEN F 0.47%
AGIO B 0.43%
CRSP C 0.42%
RARE D 0.42%
ADPT A 0.42%
MEDP F 0.4%
PTCT B 0.4%
ARGX A 0.4%
AXSM C 0.38%
ALLO D 0.37%
GRFS B 0.36%
IOVA B 0.36%
ALKS F 0.36%
KOD B 0.35%
QURE B 0.35%
FOLD B 0.32%
APLS F 0.31%
DNLI C 0.26%
ZLAB B 0.24%
IRWD F 0.24%
ARVN C 0.24%
INSM D 0.23%
FATE F 0.23%
PCRX C 0.22%
GLPG F 0.22%
ITCI A 0.21%
RGNX F 0.21%
ESPR C 0.19%
EDIT F 0.19%
LGND A 0.19%
INVA C 0.18%
ALEC D 0.18%
TBPH C 0.17%
YMAB A 0.16%
CHRS F 0.16%
HCM C 0.15%
SUPN B 0.15%
BIS Underweight 13 Positions Relative to PBE
Symbol Grade Weight
MNKD A -3.48%
PTGX B -3.18%
CPRX A -3.01%
TGTX A -2.89%
NTRA B -2.85%
BCRX A -2.83%
COLL F -2.74%
RGEN D -2.72%
QGEN D -2.64%
NVAX F -2.59%
OPK C -2.56%
VCEL D -2.28%
CDNA D -2.1%
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