BIS vs. CANC ETF Comparison

Comparison of ProShares UltraShort Nasdaq Biotechnology (BIS) to Tema Oncology ETF (CANC)
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description

The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$16.53

Average Daily Volume

13,942

Number of Holdings *

73

* may have additional holdings in another (foreign) market
CANC

Tema Oncology ETF

CANC Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from oncology. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$26.92

Average Daily Volume

2,676

Number of Holdings *

43

* may have additional holdings in another (foreign) market
Performance
Period BIS CANC
30 Days 13.36% -6.12%
60 Days 19.40% -9.26%
90 Days 19.82% -11.21%
12 Months -26.37% 15.05%
14 Overlapping Holdings
Symbol Grade Weight in BIS Weight in CANC Overlap
AGIO C 0.43% 2.71% 0.43%
AMGN F 8.14% 2.37% 2.37%
ARGX B 0.4% 4.19% 0.4%
ARVN F 0.24% 0.46% 0.24%
BGNE D 0.83% 2.3% 0.83%
BPMC B 0.48% 4.05% 0.48%
CRSP D 0.42% 2.3% 0.42%
EXEL B 0.73% 2.93% 0.73%
GH B 0.96% 2.07% 0.96%
GILD C 7.41% 5.49% 5.49%
ILMN C 5.67% 4.16% 4.16%
INCY C 2.09% 4.1% 2.09%
MRNA F 0.83% 0.72% 0.72%
REGN F 4.13% 5.25% 4.13%
BIS Overweight 59 Positions Relative to CANC
Symbol Grade Weight
VRTX D 7.21%
BIIB F 6.12%
BMRN F 1.91%
ALNY D 1.6%
VTRS A 1.35%
SNY F 1.29%
NBIX C 1.16%
SRPT F 1.15%
NVCR C 1.1%
JAZZ B 1.03%
TECH F 1.02%
IONS F 1.02%
AMRN F 0.85%
ACAD C 0.81%
ASND F 0.77%
ARWR D 0.65%
BLUE F 0.65%
BBIO F 0.51%
ALLK D 0.49%
UTHR C 0.49%
NKTR F 0.48%
SAGE F 0.48%
FGEN D 0.47%
RARE F 0.42%
ADPT C 0.42%
MEDP D 0.4%
PTCT B 0.4%
AXSM B 0.38%
ALLO F 0.37%
GRFS C 0.36%
IOVA F 0.36%
ALKS C 0.36%
KOD B 0.35%
HALO F 0.35%
QURE C 0.35%
FOLD F 0.32%
APLS F 0.31%
XNCR B 0.26%
MYGN F 0.26%
DNLI D 0.26%
ZLAB C 0.24%
IRWD F 0.24%
INSM C 0.23%
FATE F 0.23%
PCRX C 0.22%
GLPG F 0.22%
ITCI C 0.21%
RGNX D 0.21%
ESPR B 0.19%
EDIT F 0.19%
LGND C 0.19%
INVA D 0.18%
VCYT B 0.18%
ALEC F 0.18%
TBPH B 0.17%
YMAB F 0.16%
CHRS D 0.16%
HCM D 0.15%
SUPN C 0.15%
BIS Underweight 29 Positions Relative to CANC
Symbol Grade Weight
RVMD C -4.6%
MRK D -2.81%
MREO F -2.54%
SWTX C -2.14%
NVS F -2.03%
NUVL C -1.99%
DAWN D -1.9%
GMAB F -1.84%
NTLA F -1.58%
ACLX C -1.5%
EXAS D -1.45%
CLDX F -1.44%
SDGR C -1.44%
JANX C -1.43%
LEGN D -1.41%
MRUS F -1.37%
LNTH D -1.22%
NRIX C -1.15%
COGT D -0.95%
IDYA F -0.9%
BNTX C -0.89%
BCYC F -0.84%
CGEM F -0.83%
ORIC F -0.76%
RLAY F -0.69%
IMCR D -0.69%
RCUS F -0.67%
TERN F -0.6%
CGON F -0.56%
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