BIS vs. BBC ETF Comparison

Comparison of ProShares UltraShort Nasdaq Biotechnology (BIS) to Virtus LifeSci Biotech Clinical Trials ETF (BBC)
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description

The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$17.14

Average Daily Volume

13,942

Number of Holdings *

73

* may have additional holdings in another (foreign) market
BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$26.12

Average Daily Volume

1,806

Number of Holdings *

101

* may have additional holdings in another (foreign) market
Performance
Period BIS BBC
30 Days 13.36% -12.22%
60 Days 19.40% -10.51%
90 Days 19.82% -5.99%
12 Months -26.37% 38.68%
9 Overlapping Holdings
Symbol Grade Weight in BIS Weight in BBC Overlap
ALEC F 0.18% 0.71% 0.18%
ALLO F 0.37% 0.77% 0.37%
ARVN F 0.24% 0.74% 0.24%
ARWR D 0.65% 0.61% 0.61%
DNLI D 0.26% 0.98% 0.26%
EDIT F 0.19% 0.42% 0.19%
QURE C 0.35% 1.02% 0.35%
RGNX D 0.21% 0.64% 0.21%
XNCR B 0.26% 0.94% 0.26%
BIS Overweight 64 Positions Relative to BBC
Symbol Grade Weight
AMGN F 8.14%
GILD C 7.41%
VRTX D 7.21%
BIIB F 6.12%
ILMN C 5.67%
REGN F 4.13%
INCY C 2.09%
BMRN F 1.91%
ALNY D 1.6%
VTRS A 1.35%
SNY F 1.29%
NBIX C 1.16%
SRPT F 1.15%
NVCR C 1.1%
JAZZ B 1.03%
TECH F 1.02%
IONS F 1.02%
GH B 0.96%
AMRN F 0.85%
MRNA F 0.83%
BGNE D 0.83%
ACAD C 0.81%
ASND F 0.77%
EXEL B 0.73%
BLUE F 0.65%
BBIO F 0.51%
ALLK D 0.49%
UTHR C 0.49%
NKTR F 0.48%
SAGE F 0.48%
BPMC B 0.48%
FGEN D 0.47%
AGIO C 0.43%
CRSP D 0.42%
RARE F 0.42%
ADPT C 0.42%
MEDP D 0.4%
PTCT B 0.4%
ARGX B 0.4%
AXSM B 0.38%
GRFS C 0.36%
IOVA F 0.36%
ALKS C 0.36%
KOD B 0.35%
HALO F 0.35%
FOLD F 0.32%
APLS F 0.31%
MYGN F 0.26%
ZLAB C 0.24%
IRWD F 0.24%
INSM C 0.23%
FATE F 0.23%
PCRX C 0.22%
GLPG F 0.22%
ITCI C 0.21%
ESPR B 0.19%
LGND C 0.19%
INVA D 0.18%
VCYT B 0.18%
TBPH B 0.17%
YMAB F 0.16%
CHRS D 0.16%
HCM D 0.15%
SUPN C 0.15%
BIS Underweight 92 Positions Relative to BBC
Symbol Grade Weight
LBPH A -2.59%
SRRK C -2.43%
SMMT D -1.96%
WVE C -1.83%
EWTX C -1.52%
APLT C -1.43%
BLTE B -1.43%
CNTA B -1.4%
ACLX C -1.36%
VRDN D -1.33%
IRON B -1.32%
RVMD C -1.2%
NRIX C -1.19%
SAVA C -1.17%
VERA C -1.07%
ERAS C -1.06%
PTGX D -1.04%
KYMR D -1.04%
IGMS F -1.03%
PCVX D -1.02%
CRNX C -1.01%
ABUS D -1.0%
JANX C -1.0%
AKRO B -0.99%
REPL D -0.99%
KROS D -0.99%
PHVS C -0.97%
ORIC F -0.96%
ELVN D -0.96%
NUVL C -0.95%
XENE D -0.91%
RNA C -0.91%
PLRX D -0.9%
ANNX F -0.88%
IMVT F -0.87%
COGT D -0.86%
ARQT B -0.86%
VKTX F -0.83%
BEAM D -0.83%
CGON F -0.82%
CYTK F -0.82%
RCUS F -0.8%
BCYC F -0.78%
MLYS F -0.78%
NUVB C -0.76%
ETNB C -0.74%
VERV F -0.74%
DYN F -0.73%
CELC F -0.71%
MRUS F -0.7%
ABCL D -0.69%
ANAB F -0.68%
VIR D -0.67%
TERN F -0.67%
TYRA F -0.67%
MGNX F -0.66%
SNDX F -0.66%
SVRA F -0.64%
OLMA F -0.64%
KURA F -0.64%
CMPS F -0.63%
LQDA F -0.63%
LRMR D -0.6%
AUTL F -0.59%
IDYA F -0.59%
STOK F -0.59%
RLAY F -0.57%
RXRX F -0.57%
PRTA F -0.57%
SLN F -0.56%
CLDX F -0.56%
IMTX F -0.55%
CVAC F -0.55%
CGEM F -0.55%
RCKT F -0.53%
IMNM F -0.53%
NTLA F -0.47%
ITOS F -0.44%
ARCT F -0.44%
TSHA C -0.43%
PGEN F -0.42%
PRME F -0.37%
LYEL F -0.37%
FULC F -0.33%
ZNTL F -0.32%
FDMT F -0.31%
SANA F -0.29%
CABA F -0.21%
ALXO F -0.13%
HLVX F -0.11%
AVTE D -0.09%
SCLX F -0.09%
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