BBC vs. BIS ETF Comparison

Comparison of Virtus LifeSci Biotech Clinical Trials ETF (BBC) to ProShares UltraShort Nasdaq Biotechnology (BIS)
BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description

The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$27.10

Average Daily Volume

4,086

Number of Holdings *

90

* may have additional holdings in another (foreign) market
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$19.00

Average Daily Volume

7,652

Number of Holdings *

75

* may have additional holdings in another (foreign) market
Performance
Period BBC BIS
30 Days -5.29% 7.60%
60 Days -13.57% 13.81%
90 Days 3.98% 9.60%
12 Months 17.51% -1.48%
11 Overlapping Holdings
Symbol Grade Weight in BBC Weight in BIS Overlap
ALEC D 0.56% 0.18% 0.18%
ALLK F 0.28% 0.49% 0.28%
ALLO F 1.05% 0.37% 0.37%
ARVN D 0.81% 0.24% 0.24%
ARWR D 0.7% 0.65% 0.65%
DNLI D 0.59% 0.26% 0.26%
EDIT F 0.43% 0.19% 0.19%
IOVA C 1.3% 0.36% 0.36%
QURE F 0.5% 0.35% 0.35%
RGNX D 0.65% 0.21% 0.21%
XNCR B 0.73% 0.26% 0.26%
BBC Overweight 79 Positions Relative to BIS
Symbol Grade Weight
ALPN A 2.89%
VKTX B 2.86%
RNA A 2.65%
VERA C 2.27%
DYN C 1.82%
SANA B 1.72%
CGEM A 1.66%
CYTK D 1.52%
LQDA C 1.5%
MGNX C 1.48%
KROS C 1.38%
MRUS B 1.37%
NRIX D 1.34%
GERN A 1.34%
KURA C 1.33%
BCYC B 1.28%
FDMT C 1.26%
COGT D 1.19%
KYMR C 1.19%
SMMT B 1.19%
KRYS C 1.18%
MLYS C 1.17%
RVMD A 1.17%
PTGX D 1.09%
CRNX A 1.07%
INBX C 1.05%
LYEL C 1.02%
IGMS D 1.0%
DAWN A 0.99%
ALXO A 0.99%
IDYA C 0.97%
PGEN C 0.94%
ARDX C 0.93%
ACLX D 0.9%
IMTX D 0.9%
CMPS C 0.9%
SNDX C 0.89%
CLDX C 0.88%
PHAT D 0.86%
ITOS B 0.86%
PCVX C 0.85%
ANAB B 0.85%
ARCT D 0.84%
XENE C 0.84%
MORF F 0.82%
ORIC D 0.81%
AKRO F 0.8%
MDGL C 0.78%
RCUS D 0.74%
DVAX D 0.73%
NUVL C 0.72%
BLTE C 0.71%
RCKT F 0.71%
ZNTL F 0.71%
REPL F 0.7%
ETNB F 0.7%
OLMA D 0.69%
RXRX D 0.68%
VIR F 0.68%
BEAM F 0.67%
TGTX B 0.67%
SRRK C 0.67%
BMEA F 0.66%
PLRX D 0.63%
NVAX F 0.62%
VRDN D 0.62%
TERN F 0.61%
ABCL F 0.61%
SAVA B 0.58%
IMVT D 0.57%
NTLA D 0.57%
CRBU F 0.55%
CABA D 0.55%
RLAY D 0.5%
PRTA F 0.45%
VERV F 0.41%
IRON F 0.39%
CVAC F 0.38%
RAPT F 0.35%
BBC Underweight 64 Positions Relative to BIS
Symbol Grade Weight
AMGN B -8.14%
GILD F -7.41%
VRTX C -7.21%
BIIB C -6.12%
ILMN D -5.67%
REGN C -4.13%
INCY D -2.09%
BMRN D -1.91%
ALNY D -1.6%
VTRS C -1.35%
SNY A -1.29%
NBIX A -1.16%
SRPT B -1.15%
NVCR F -1.1%
JAZZ F -1.03%
TECH B -1.02%
IONS D -1.02%
GH F -0.96%
AMRN F -0.85%
MRNA A -0.83%
BGNE C -0.83%
ACAD D -0.81%
ASND C -0.77%
EXEL B -0.73%
BLUE F -0.65%
BBIO D -0.51%
UTHR A -0.49%
NKTR A -0.48%
SAGE F -0.48%
BPMC A -0.48%
FGEN F -0.47%
DCPH A -0.43%
AGIO A -0.43%
CRSP F -0.42%
RARE D -0.42%
ADPT F -0.42%
MEDP B -0.4%
PTCT B -0.4%
ARGX D -0.4%
AXSM B -0.38%
GRFS D -0.36%
ALKS F -0.36%
KOD D -0.35%
HALO C -0.35%
FOLD D -0.32%
APLS F -0.31%
MYGN C -0.26%
ZLAB F -0.24%
IRWD D -0.24%
INSM D -0.23%
FATE D -0.23%
PCRX D -0.22%
GLPG F -0.22%
ITCI B -0.21%
ESPR C -0.19%
LGND C -0.19%
INVA A -0.18%
VCYT D -0.18%
TBPH D -0.17%
YMAB B -0.16%
CHRS F -0.16%
HCM A -0.15%
NGM D -0.15%
SUPN C -0.15%
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