SBIO vs. CANC ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to Tema Oncology ETF (CANC)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$37.20

Average Daily Volume

8,661

Number of Holdings *

83

* may have additional holdings in another (foreign) market
CANC

Tema Oncology ETF

CANC Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from oncology. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$26.52

Average Daily Volume

2,676

Number of Holdings *

43

* may have additional holdings in another (foreign) market
Performance
Period SBIO CANC
30 Days -5.42% -6.12%
60 Days -4.09% -9.26%
90 Days 0.49% -11.21%
12 Months 48.12% 15.05%
12 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in CANC Overlap
ACLX C 3.19% 1.5% 1.5%
AGIO C 2.05% 2.71% 2.05%
ARVN F 1.06% 0.46% 0.46%
CGON F 1.57% 0.56% 0.56%
CLDX F 1.06% 1.44% 1.06%
COGT D 0.69% 0.95% 0.69%
DAWN D 0.82% 1.9% 0.82%
IDYA F 1.53% 0.9% 0.9%
IMCR D 1.07% 0.69% 0.69%
MRUS F 2.21% 1.37% 1.37%
NTLA F 0.94% 1.58% 0.94%
RCUS F 0.95% 0.67% 0.67%
SBIO Overweight 71 Positions Relative to CANC
Symbol Grade Weight
CORT B 3.66%
KRYS C 3.39%
RNA C 3.29%
ALKS C 3.15%
CRNX C 2.95%
IMVT F 2.66%
DNLI D 2.36%
PTCT B 2.02%
XENE D 2.01%
VRNA B 1.98%
FOLD F 1.95%
EWTX C 1.92%
ACAD C 1.89%
VERA C 1.82%
ZLAB C 1.79%
VCEL B 1.73%
PTGX D 1.61%
GERN D 1.48%
MIRM B 1.47%
KROS D 1.4%
LBPH A 1.4%
AKRO B 1.32%
MNKD C 1.26%
IRON B 1.21%
GLPG F 1.19%
TARS C 1.16%
BCRX D 0.99%
XNCR B 0.98%
SNDX F 0.93%
SPRY C 0.88%
VRDN D 0.84%
KURA F 0.83%
AUPH B 0.78%
PHVS C 0.76%
APLT C 0.72%
ETNB C 0.57%
LQDA F 0.54%
PLRX D 0.53%
PRTA F 0.52%
ERAS C 0.51%
REPL D 0.5%
IRWD F 0.44%
AVXL B 0.42%
ANNX F 0.4%
MLYS F 0.39%
ALT C 0.37%
OLMA F 0.37%
ANAB F 0.36%
FLGT F 0.35%
ALLO F 0.35%
CELC F 0.34%
YMAB F 0.34%
URGN F 0.34%
SVRA F 0.34%
FULC F 0.33%
TBPH B 0.32%
FDMT F 0.31%
GHRS C 0.31%
ARCT F 0.31%
AURA C 0.3%
ALEC F 0.28%
CMPS F 0.23%
ACIU D 0.22%
VNDA C 0.2%
ITOS F 0.19%
STRO F 0.17%
ALDX D 0.17%
ZNTL F 0.17%
ENTA F 0.14%
INZY F 0.12%
HLVX F 0.06%
SBIO Underweight 31 Positions Relative to CANC
Symbol Grade Weight
GILD C -5.49%
REGN F -5.25%
RVMD C -4.6%
ARGX B -4.19%
ILMN C -4.16%
INCY C -4.1%
BPMC B -4.05%
EXEL B -2.93%
MRK D -2.81%
MREO F -2.54%
AMGN F -2.37%
BGNE D -2.3%
CRSP D -2.3%
SWTX C -2.14%
GH B -2.07%
NVS F -2.03%
NUVL C -1.99%
GMAB F -1.84%
EXAS D -1.45%
SDGR C -1.44%
JANX C -1.43%
LEGN D -1.41%
LNTH D -1.22%
NRIX C -1.15%
BNTX C -0.89%
BCYC F -0.84%
CGEM F -0.83%
ORIC F -0.76%
MRNA F -0.72%
RLAY F -0.69%
TERN F -0.6%
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