Integrin Stocks List
Symbol | Grade | Name | % Change | |
---|---|---|---|---|
PLRX | D | Pliant Therapeutics, Inc. | 10.25 | |
MORF | F | Morphic Holding, Inc. | 3.77 |
Related Industries: Biotechnology
Symbol | Grade | Name | Weight | |
---|---|---|---|---|
SBIO | D | ALPS Medical Breakthroughs ETF | 1.46 | |
BBC | D | Virtus LifeSci Biotech Clinical Trials ETF | 1.43 | |
XBI | C | SPDR S&P Biotech ETF | 0.76 | |
XPH | D | SPDR S&P Pharmaceuticals ETF | 0.63 | |
BTEC | C | Principal Healthcare Innovators Index ETF | 0.53 |
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- Integrin
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, organization of the intracellular cytoskeleton, and movement of new receptors to the cell membrane. The presence of integrins allows rapid and flexible responses to events at the cell surface (e.g. signal platelets to initiate an interaction with coagulation factors).
Several types of integrins exist, and one cell may have multiple different types on its surface. Integrins are found in all animals while integrin-like receptors are found in plant cells.Integrins work alongside other proteins such as cadherins, the immunoglobulin superfamily cell adhesion molecules, selectins and syndecans, to mediate cell–cell and cell–matrix interaction. Ligands for integrins include fibronectin, vitronectin, collagen and laminin.
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