XBI vs. BIS ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to ProShares UltraShort Nasdaq Biotechnology (BIS)
XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$94.89

Average Daily Volume

11,450,957

Number of Holdings *

125

* may have additional holdings in another (foreign) market
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$17.58

Average Daily Volume

29,115

Number of Holdings *

77

* may have additional holdings in another (foreign) market
Performance
Period XBI BIS
30 Days -7.78% 7.75%
60 Days 7.54% -0.53%
90 Days 6.27% -1.85%
12 Months 24.36% -12.50%
40 Overlapping Holdings
Symbol Grade Weight in XBI Weight in BIS Overlap
ACAD F 0.79% 0.81% 0.79%
AGIO C 0.74% 0.43% 0.43%
ALEC F 0.19% 0.18% 0.18%
ALKS F 0.93% 0.36% 0.36%
ALLO D 0.38% 0.37% 0.37%
ALNY F 0.99% 1.6% 0.99%
AMGN D 1.02% 8.14% 1.02%
APLS F 0.93% 0.31% 0.31%
ARWR F 0.85% 0.65% 0.65%
BBIO D 1.01% 0.51% 0.51%
BIIB F 1.0% 6.12% 1.0%
BMRN D 0.99% 1.91% 0.99%
BPMC C 0.99% 0.48% 0.48%
CRSP D 0.95% 0.42% 0.42%
DCPH D 0.37% 0.43% 0.37%
DNLI D 1.01% 0.26% 0.26%
EDIT F 0.7% 0.19% 0.19%
EXEL B 1.09% 0.73% 0.73%
FATE C 0.6% 0.23% 0.23%
FOLD F 0.96% 0.32% 0.32%
GILD F 0.98% 7.41% 0.98%
HALO C 0.97% 0.35% 0.35%
INCY F 0.97% 2.09% 0.97%
INSM D 0.96% 0.23% 0.23%
IONS D 0.98% 1.02% 0.98%
IOVA C 0.99% 0.36% 0.36%
IRWD F 1.01% 0.24% 0.24%
MRNA C 1.02% 0.83% 0.83%
MYGN C 0.61% 0.26% 0.26%
NBIX B 1.04% 1.16% 1.04%
PTCT D 0.98% 0.4% 0.4%
RARE D 0.93% 0.42% 0.42%
REGN B 1.01% 4.13% 1.01%
RGNX C 0.45% 0.21% 0.21%
SAGE F 0.86% 0.48% 0.48%
SRPT D 1.02% 1.15% 1.02%
UTHR C 0.99% 0.49% 0.49%
VCYT F 0.73% 0.18% 0.18%
VRTX D 1.02% 7.21% 1.02%
XNCR C 0.58% 0.26% 0.26%
XBI Overweight 85 Positions Relative to BIS
Symbol Grade Weight
DYN C 1.11%
ALPN C 1.08%
CRNX C 1.07%
IMVT D 1.06%
CERE B 1.04%
NTRA B 1.04%
EXAS D 1.04%
RVMD C 1.02%
SWTX C 1.02%
ACLX C 1.01%
MDGL C 1.01%
IDYA D 1.01%
CYTK D 1.01%
KRYS C 1.0%
ABBV C 1.0%
RCKT D 1.0%
VKTX C 0.99%
RYTM D 0.98%
TWST D 0.97%
RXRX D 0.96%
KYMR C 0.95%
BCRX F 0.95%
NUVL D 0.95%
DVAX D 0.94%
PCVX D 0.94%
SNDX C 0.94%
BEAM C 0.94%
NTLA D 0.93%
TGTX D 0.92%
ARQT C 0.92%
KROS C 0.91%
ARDX D 0.91%
BMEA F 0.9%
ALT D 0.89%
VCEL C 0.89%
CPRX C 0.89%
NVAX D 0.88%
GERN C 0.88%
CLDX C 0.87%
PRTA F 0.86%
VRDN F 0.85%
AKRO D 0.84%
MORF D 0.84%
VERA C 0.83%
CCCC C 0.8%
INBX D 0.78%
MIRM F 0.76%
PTGX C 0.75%
KURA C 0.73%
IRON D 0.7%
CABA D 0.69%
SRRK C 0.66%
RCUS D 0.65%
VERV D 0.63%
MGNX D 0.6%
FDMT C 0.58%
REPL D 0.58%
ETNB D 0.58%
ARCT D 0.57%
TVTX F 0.53%
RNA C 0.53%
COGT D 0.52%
SANA C 0.5%
VIR F 0.49%
ADMA B 0.47%
ZNTL D 0.45%
RLAY F 0.41%
CDMO F 0.4%
CDNA D 0.4%
OLMA F 0.38%
AVXL F 0.38%
MNKD C 0.38%
DAWN C 0.32%
KNSA C 0.31%
CRBU F 0.31%
NRIX C 0.3%
MDXG D 0.26%
SMMT D 0.25%
ANAB D 0.24%
MRSN D 0.2%
ORIC C 0.18%
CGEM C 0.17%
VYGR C 0.12%
SPRY C 0.11%
RCEL D 0.09%
XBI Underweight 37 Positions Relative to BIS
Symbol Grade Weight
ILMN F -5.67%
VTRS D -1.35%
SNY F -1.29%
NVCR F -1.1%
JAZZ D -1.03%
TECH D -1.02%
GH F -0.96%
AMRN F -0.85%
BGNE D -0.83%
ASND C -0.77%
BLUE D -0.65%
ALLK F -0.49%
NKTR C -0.48%
FGEN D -0.47%
MRTX C -0.46%
ADPT F -0.42%
MEDP B -0.4%
ARGX D -0.4%
AXSM D -0.38%
GRFS F -0.36%
KOD C -0.35%
QURE F -0.35%
KRTX A -0.33%
ZLAB F -0.24%
ARVN D -0.24%
PCRX F -0.22%
GLPG F -0.22%
ITCI C -0.21%
ESPR D -0.19%
LGND D -0.19%
INVA D -0.18%
TBPH F -0.17%
YMAB C -0.16%
CHRS F -0.16%
HCM C -0.15%
NGM D -0.15%
SUPN C -0.15%
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