SPBC vs. SBIO ETF Comparison

Comparison of Simplify U.S. Equity PLUS GBTC ETF (SPBC) to ALPS Medical Breakthroughs ETF (SBIO)
SPBC

Simplify U.S. Equity PLUS GBTC ETF

SPBC Description

The investment seeks long-term capital appreciation. Under normal circumstances, the fund will invest at least 80% of its net assets (plus any borrowings for investment purposes) in equity securities of U.S. companies and the Grayscale Bitcoin Trust. The fund invests in equity securities of U.S. companies through exchange-traded futures contracts, equity securities of U.S. companies and ETFs that primarily invest in the equity securities of U.S. companies. The fund invests up to 15% of its total assets in the Grayscale Bitcoin Trust.

Grade (RS Rating)

Last Trade

$33.82

Average Daily Volume

10,635

Number of Holdings *

1

* may have additional holdings in another (foreign) market
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$35.75

Average Daily Volume

13,427

Number of Holdings *

85

* may have additional holdings in another (foreign) market
Performance
Period SPBC SBIO
30 Days 6.54% -7.59%
60 Days 14.87% 9.00%
90 Days 19.32% 8.53%
12 Months 52.87% 30.92%
0 Overlapping Holdings
Symbol Grade Weight in SPBC Weight in SBIO Overlap
SPBC Overweight 1 Positions Relative to SBIO
Symbol Grade Weight
GBTC C 12.91%
SPBC Underweight 85 Positions Relative to SBIO
Symbol Grade Weight
CERE B -4.62%
VKTX C -4.46%
PCVX D -4.41%
RVMD C -3.21%
ALKS F -2.71%
AXSM D -2.31%
ACLX C -2.29%
SWTX C -2.28%
CBAY A -2.24%
CRNX C -2.11%
IDYA D -2.03%
XENE D -1.97%
IMCR D -1.86%
ACAD F -1.83%
ARVN D -1.78%
DNLI D -1.76%
ALPN C -1.64%
MRUS C -1.63%
NTLA D -1.6%
CLDX C -1.59%
CORT D -1.54%
SMMT D -1.5%
KROS C -1.49%
RYTM D -1.47%
VERA C -1.42%
VCEL C -1.36%
GLPG F -1.33%
CPRX C -1.18%
SNDX C -1.17%
RNA C -1.16%
GERN C -1.09%
MORF D -1.04%
ZLAB F -1.03%
AGIO C -1.02%
FDMT C -1.01%
INBX D -1.0%
PTGX C -0.99%
KURA C -0.98%
EWTX D -0.95%
RCUS D -0.94%
IRON D -0.89%
AKRO D -0.88%
IRWD F -0.85%
XNCR C -0.84%
PRTA F -0.83%
VIR F -0.82%
DAWN C -0.79%
VRNA F -0.78%
MNKD C -0.77%
TARS C -0.76%
DCPH D -0.75%
LQDA B -0.74%
MIRM F -0.73%
MDXG D -0.72%
VRDN F -0.71%
BCRX F -0.68%
ETNB D -0.64%
ZNTL D -0.59%
MGNX D -0.57%
PLRX F -0.55%
ARCT D -0.53%
SPRY C -0.52%
KNSA C -0.48%
AUPH F -0.44%
ALLO D -0.44%
AVTE C -0.43%
SVRA D -0.4%
OPK F -0.39%
ANAB D -0.39%
OLMA F -0.38%
BMEA F -0.37%
CMPS D -0.37%
TVTX F -0.37%
ALEC F -0.36%
FULC C -0.36%
MLYS C -0.32%
REPL D -0.3%
ITOS D -0.25%
AVXL F -0.25%
AURA D -0.25%
INZY C -0.22%
ENTA C -0.19%
RAPT F -0.18%
VNDA F -0.14%
RPHM D -0.03%
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