SBIO vs. LABD ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to Direxion Daily S&P Biotech Bear 3X Shares (LABD)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$34.09

Average Daily Volume

11,436

Number of Holdings *

84

* may have additional holdings in another (foreign) market
LABD

Direxion Daily S&P Biotech Bear 3X Shares

LABD Description The investment seeks daily investment results, before fees and expenses, of 300% of the inverse of the performance of the S&P Biotechnology Select Industry Index. The index is provided by Standard & Poor's and includes domestic companies from the biotechnology industry. The fund normally creates short positions by investing at least 80% of its assets in: swap agreements; options on securities and indices; forward contracts; short positions; reverse repurchase agreements; ETFs; and other financial instruments that, in combination, provide inverse leveraged and unleveraged exposure to the S&P Biotechnology Select Industry Index ("index"). It is non-diversified.

Grade (RS Rating)

Last Trade

$7.95

Average Daily Volume

14,384,254

Number of Holdings *

80

* may have additional holdings in another (foreign) market
Performance
Period SBIO LABD
30 Days 5.37% -21.13%
60 Days -1.11% 2.14%
90 Days -5.88% -1.26%
12 Months 8.03% -40.76%
19 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in LABD Overlap
ACAD F 1.6% 1.68% 1.6%
AGIO B 1.18% 1.37% 1.18%
ALEC F 0.32% 0.25% 0.25%
ALKS F 2.59% 1.21% 1.21%
ALLO F 0.31% 0.54% 0.31%
ANAB C 0.45% 0.53% 0.45%
CPRX C 1.18% 0.53% 0.53%
DCPH A 1.31% 1.01% 1.01%
DNLI C 1.66% 0.28% 0.28%
ENTA F 0.17% 0.47% 0.17%
IRWD F 0.67% 0.75% 0.67%
MGNX F 0.58% 0.25% 0.25%
NTLA D 1.53% 0.29% 0.29%
OPK D 0.56% 0.35% 0.35%
TVTX F 0.32% 0.33% 0.32%
VCEL C 1.5% 0.34% 0.34%
VKTX D 5.37% 0.38% 0.38%
VNDA C 0.18% 0.35% 0.18%
XNCR C 0.92% 0.49% 0.49%
SBIO Overweight 65 Positions Relative to LABD
Symbol Grade Weight
CERE D 4.9%
PCVX C 4.52%
RVMD B 3.94%
ALPN A 2.71%
CRNX B 2.45%
AXSM C 2.23%
SMMT C 2.14%
XENE F 2.05%
SWTX D 2.02%
IDYA D 1.91%
IMCR F 1.9%
ACLX D 1.78%
CORT C 1.76%
CLDX D 1.69%
MRUS D 1.67%
RYTM D 1.48%
VERA D 1.48%
ARVN D 1.39%
RNA B 1.38%
GERN C 1.35%
KROS D 1.32%
ZLAB D 1.32%
GLPG F 1.22%
EWTX C 1.19%
SNDX D 1.19%
INBX D 1.05%
PTGX C 1.05%
KURA C 1.01%
MORF F 0.93%
RCUS D 0.93%
DAWN C 0.91%
VIR D 0.82%
FDMT D 0.81%
TARS C 0.81%
MIRM F 0.77%
VRNA F 0.76%
AKRO F 0.75%
PRTA F 0.75%
MNKD C 0.74%
BCRX C 0.7%
MDXG C 0.68%
LQDA D 0.6%
ZNTL F 0.57%
VRDN F 0.56%
SPRY D 0.54%
ETNB F 0.54%
PLRX D 0.53%
KNSA C 0.52%
AUPH D 0.48%
IRON F 0.47%
ARCT D 0.46%
SVRA D 0.44%
AVTE D 0.38%
MLYS C 0.37%
OLMA F 0.35%
CMPS F 0.35%
FULC F 0.3%
ITOS B 0.28%
BMEA F 0.26%
REPL F 0.26%
AURA F 0.24%
AVXL D 0.2%
INZY F 0.18%
RAPT F 0.1%
RPHM D 0.04%
SBIO Underweight 61 Positions Relative to LABD
Symbol Grade Weight
EXEL F -1.91%
BMRN F -1.89%
BLUE F -1.87%
VRTX B -1.84%
SAGE F -1.8%
UTHR A -1.78%
REGN B -1.77%
AMGN B -1.75%
ALNY D -1.73%
EXAS F -1.73%
ABBV D -1.72%
SRPT C -1.66%
BIIB D -1.65%
IONS F -1.64%
GILD F -1.64%
NBIX B -1.62%
BPMC C -1.61%
INCY D -1.51%
RARE F -1.49%
MRNA C -1.47%
LGND C -1.46%
ARWR F -1.45%
BHVN D -1.42%
PTCT C -1.4%
FOLD F -1.38%
APLS F -1.24%
MYGN B -1.08%
NTRA B -1.08%
IOVA F -1.07%
FGEN F -1.05%
RGNX F -1.05%
CHRS F -0.99%
EBS C -0.96%
CDNA B -0.93%
HRTX B -0.84%
INSM F -0.81%
KPTI D -0.79%
ESPR D -0.79%
ALLK D -0.76%
VCYT D -0.72%
HALO B -0.71%
FATE F -0.67%
EDIT F -0.66%
PBYI F -0.65%
MDGL D -0.59%
TGTX D -0.55%
ADVM F -0.55%
SGMO D -0.48%
EGRX F -0.42%
GTHX C -0.42%
ATRA F -0.41%
ANIK D -0.37%
KOD F -0.29%
BBIO D -0.29%
PGEN D -0.29%
KRYS D -0.28%
GOSS F -0.27%
VYGR F -0.26%
CYTK F -0.25%
DVAX F -0.24%
YMAB F -0.24%
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